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Choughs and irises. Anthropology of tourism, space and identity in Morocco
Konopíková, Michaela ; Soukup, Martin (advisor) ; Bláha, Jan Daniel (referee) ; Sokolíčková, Zdenka (referee)
The dissertation project is based on a long-term fieldwork among the Berber community in the Moroccan High Atlas Mountains. It looks at the transformation of the local environment since new discursive practices are emerging as a result of an interference of the global economy, environmentalism and developmental policies. Following Appadurai, the thesis raises a question of locality in contemporary world and neighborhoods, which are imagined, produced, and maintained against some sort of ground while the context-generative dimension of neighborhoods provides a theoretical angle on the relationship of global and local realities with the idea of culturally hybridized world. Together with Appadurai, the thesis deals with "what locality might mean in a situation where the nation-state faces particular sorts of transnational destabilization." The thesis has thus two main aims. (1) After describing the structural conditions in which the tourism industry in the mountains operates, (2) it will discuss the limitations of the locals' responses to the global market, or more broadly the impacts of globalization. It is necessary to establish a framework, which would connect the large- scale and small-scale processes and identify the concept of their dialectical relationships. Through such a reading, the thesis...
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Non-traditional methods of drug administration in anesthesiology and emergency medicine
Kurzová, Alice ; Málek, Jiří (advisor) ; Bláha, Jan (referee) ; Gabrhelík, Tomáš (referee)
1 SUMMARY Introduction The thesis is focused on the research of efficacy and side effects of non-traditional, i.e. nasal administration of oxytocin and nasal and intramuscular administration of remifentanil. Nasal administration has the advantage of being non-invasive and useful in situations with difficult vein access (young children, extensive burns, terrorist attacks and battlefields). The dissertation has two parts that are closely related: nasal, intramuscular and conjunctival administration of remifentanil, nasal and intramuscular administration of oxytocin. Remifentanil is an ultra-short- acting opioid that is registered for intravenous administration only. Its main advantage over other opioids is its rapid metabolism after intravenous administration and absent accumulation even after prolonged infusion. Remifentanil is the only opioid for which, with the exception of two papers, intranasal administration has not been described yet; data on intramuscular and conjunctival administration are completely lacking. Oxytocin is a hormone that is used therapeutically primarily for its peripheral effects in the uterus and breast during pregnancy. However, other central effects have also been observed, i.e. anxiolytic effect, reduction of social stress levels and increase in empathy. It can be useful in...
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Analysis of performance development in the Czech Republic in the discipline 3000 m steeplechase men from 1945 to the present
BLÁHA, Jan
Bibliographical identification Title of the graduation thesis: Analysis of performance development in the Czech Republic in the course 3 000m steeplechase men from 1945 to the present Author's first name and surname: Bc. Jan Bláha Field of study: B7401 Physical Education Department: Department of Sports studies Supervisor: PhDr. Petr Bahenský, Ph.D. The year of presentation: 2022 Abstract: This diploma thesis deals with the analyses of performance development of Czechoslovakian runners on the course of 3000 meters steeplechase between years 1945 and 1992, and then Czech runners from 1993 until the present times (2021). The aim of this graduation thesis is to discover how the performance has evolved throughout the years and when we can observe its most significant increase. In the analytic part of the thesis the basic characteristics of 3000 meters steeplechase were described and examined with regards to the historic roots of this discipline, interpretation of valid rules, somatic and physiological preconditions of runners, stages of sports preparation, development of sports training and suitability and influence of high-altitude preparation within 3000 meters steeplechase training. The synthetic part contains charts and graphs that were obtained through data analysis from historic athletic charts and yearbooks.
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The impact of the cartographic method on students' map skills level
Havelková, Lenka ; Hanus, Martin (advisor) ; Bláha, Jan Daniel (referee)
The presented diploma thesis focuses on the map skills' problematic, which is currently becoming widespread in the Czech research environment. In contrast to the previous empirical studies, this thesis is devoted to the thematic map skills and their level of development among students of grammar schools and geographically oriented branches of university studies. Due to the significant differences between used cartographic methods of visualization on thematic maps the main aim of this diploma thesis is to identify and explain used cartographic method's influence on the level of these important skills. To achieve this aim, it was necessary to focus on different parts of the curriculum (intended, implemented, learned) and to use several scientific methods because this topic hasn't been well established yet and therefore only few theoretical and empirical studies dealt with this specific issue. Firstly, the review of literature focused on thematic cartography, map skills and on identifying their level of development among students was done. Due to the lack of specialized resources the model of thematic map skills was created. This specific model was further used during didactic test's designing and also for its results' interpretation. Similarly for the creation of appropriate didactic test -...
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Use of Mental Maps of Users in Assessment of Cartographic Works
Novotná, Kateřina ; Bláha, Jan Daniel (advisor) ; Hudeček, Tomáš (referee)
Use of mental maps of users in assessment of cartographic works Abstract The aim of this thesis is to propose and practical apply the alternative methodics of assessment of cartographic works. The thesis is processed in the terms of project of Grant Agency of the Charles University Mental Maps: subject and means for assessment. The adjoining aim of this study is then to test which of the assessed tourist maps is the most user friendly. As the method for data acquiring the questionnaire investigation methodology has been chosen. The basic for the assessment of cartographic works are in the case of this study of mental maps of lynch type. Theoretical part is devoted to Mental and Cognitive Maps as well as to the ways of cartographic works assessment. Space is also devoted to the methodology of assessment cartographic works itself. There has been defined the subject of assessment together with the statement of hypotheses and the aims of thesis. Practical application of the proposal methodology and assessment the results has been composed from several parts. First the tourist maps have been assessed by the expert himself. Afterwords another assessment has started with the use of mental maps. This assessment has been composed of the phase of preparation where the questionnaire itself was being created. Then it...
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Cultural Aspects of Cartographic Creation: Use of Mental Maps in Cross-cultural Research
Bláha, Jan Daniel ; Soukup, Martin (advisor) ; Soukup, Václav (referee)
Cultural Aspects of Cartographic Creation: Use of Mental Maps in Cross-cultural Research Abstract: Diploma thesis deals with study of interdisciplinary issue of cultural aspects of cartographic creation. The first part of the work consists of theoretical introduction dealing with the map con- tent, map stylistics and map language, in which maps show the greatest cultural differences. The map figures here in a role of the image of reality and visual manifestation of culture. The analogy between a map and a classical language (linguistic anthropology) and the analogy between early maps and primitive cultures' maps are described. Beside the language, as determinants of the human spatial perception and other categories related to the map creation could be mentioned the environment, the experiences and the society, in which man lives. Several examples of so- called cultural map styles, especially from Australia and Oceania, are introduced as well. In the methodical part of the work in connection with cultural-anthropological research a method of cognitive maps, respectively mental maps of map users and map makers is discussed in detail. Just these maps are suitable to explore the cultural particularities of cartographic creation. The application part of the work presents the results of field research of mental...
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Recombinant expression of transcription factor TEAD1.
Řeháková, Jana ; Novák, Petr (advisor) ; Bláha, Jan (referee)
TEAD1 is one of the members of the TEAD transcription factor family. This transcription factor is very important, for example for development of organs. The structure of the entire TEAD1 transcription factor is not now yet known. Nevertheless, structure of two important domains are known. The TEA binding domain, which is important for the binding of the transcription factor TEAD1 to DNA, and the transactivation domain, to which coactivators bind. TEAD1 binds to DNA and upon coactivator bind it affects the transcription of various genes. Genes, that are affected by the transcription factor TEAD1 includes genes regulating proliferation, differentiation and apoptosis of cells. TEAD1 is also the target of the Hippo signalling pathway, which is active in adulthood and prevents abnormal growth of organs. Important for the activity of transcriptional factor TEAD1 are post-translation modifications, such as palmitoylation and phosphorylation. To discover the entire structure of the transcriptional factor TEAD1 and the way it interacts with DNA, the transcriptional factor TEAD1 was prepared recombinationally by expression in cells of Escherichia coli bacteria. Suitable conditions for production of the transcriptional factor TEAD1 were found and the cleavage of the histidine tag by thrombin was performed....
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