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National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Comparison of metabolic parameters, hormonal level changes and cardiovascular risk in patients with gestational diabetes with healthy pregnant controls using ECG mapping method and other noninvasive cardiologic methodics
 Žákovičová, Eva ; Charvát, František (advisor) ; Ošťádal, Petr (referee) ; Rušavý, Zdeněk (referee)
History of GDM not only increases the risk of developing type 2 diabetes mellitus, but also the risk of cardiovascular disease that is independent of type 2 DM. Hyperglycemia leads to significant electrophysiological, functional and structural changes in the cardiovascular system and they are interrelated. One of our main goals was to evaluate metabolic and hormonal changes and detect changes in the cardiovascular system and assess their mutual relations in condition of optimal metabolic control using a predetermined treatment algorithm. Echocardiography findings in our group of patients with GDM confirm the presence of incipient structural changes in left ventricular (significantly thicker IVS, PWD and RWT) compared to the control group. The original finding is that, under optimal compensation of diabetes any of monitored parameters of left ventricular diastolic function have not been changed. Furthermore, we found that complex metabolic care with optimal values of blood sugar together with weight gain monitoring in women with GDM leads to improvement of the 24-hour blood pressure profile without increased prevalence of non-dipper women and that nocturnal decline in BP depends on fasting plasma glucose. ECG body surface mapping did not show statistically significant changes in depolarization and...
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