National Repository of Grey Literature 26 records found  previous11 - 20next  jump to record: Search took 0.00 seconds. 
The role of proto-oncogene crk in invasiveness
Tomášová, Lea ; Rösel, Daniel (advisor) ; Ševčík, Jan (referee)
Proto-oncogene Crk was identified as an oncogenic product of an avian retrovirus in 1988. It is an adaptor protein containing SH2 and SH3 binding domains. Thanks to these domains Crk facilitates protein-protein interactions and therefore plays a crucial role in signal transduction. Crk forms signal complexes with several proteins and hence impacts many cellular processes, among them cell migration, tumorigenezis and invasion of the surrounding tissues. The increased invasiveness allows the tumour cells to detach from the primary tumour and form metastasis which is very problematic feature of cancer. Overexpression of Crk was observed in several tumour tissues, it correlates with an aggressive and metastatic phenotype of the tumours. The subject of this thesis is to describe the mechanisms of how Crk can regulate cellular motility and invasiveness.
The Evaluation of the Financial Situation of a Company
Zouhar, Jan ; Ševčík, Jan (referee) ; Pavláková Dočekalová, Marie (advisor)
The dissertation aims on evaluating the financial situation of the company ITAB Shop Concept CZ, a.s. Depending on data gathered by the financial analysis, it includes suggestions for better optimalization of examined financial ratio and overall improvement of company’s financial situation.
Solution of Receivables in Capital Company
Teturová, Hana ; ing.Jan Ševčík (referee) ; Ing.Jan Ševčík (referee) ; Fedorová, Anna (advisor)
The topic of this thesis work is solution of receivables. At first we make to charted present status care of receivables in capital company. After analysis suggestions follow to innovation as prevention and solution creation non-paid receivables.
Optimizing of electronic bussiness of firm GAME LAND s.r.o.
Smrž, Marek ; Ševčík, Jan (referee) ; Kříž, Jiří (advisor)
This bachelor´s thesis describes and evaluates electronic business of a medium size company which the sphere of business is information technology. Paper is divided into two parts and contains eleven pictures. First section describes the current state of electronic business regarding its content, functionality and graphic user interface. Second section contains improvement concepts for particular fields that will eventually help with general optimization of the e-business. Innovation concepts are strongly customer-oriented and they will improve the usability of web pages and contribute on gain enhancement.
Monolithic milling tools with PVD coatings and their use
Ševčík, Jan ; Sliwková, Petra (referee) ; Jaroš, Aleš (advisor)
The bachelor thesis deals with the monolithic milling tools carbide on the surface which is deposited by a thin layer of rating on. First of all, the thesis describes the method of milling, the basic division of milling operations and milling tools, power analysis tool load. Then, it is analyzed problems of cemented carbides, its production, properties and dividing into groups. After that it is described characteristic of coating methods, especially the PVD method, and its modifications. The last part is devoted to producer’s offers of coated monolithic mills. There are introduced few selected tools and described its characteristics, geometry and application suitability.
Multifunctional building - Houbalova - construction technology project
Ševčík, Jan ; Čech, Václav (referee) ; Henková, Svatava (advisor)
The subject of this thesis is the solution of building technology project poly-functional complex with a focus on execution of construction. Gross building is designed reinforced concrete skeleton combined with masonry. Technology will be developed Code for reinforced concrete monolithic frame and masonry. On the techno-logical stage it will be processed inspection and test plan and the balance of the major sources for the implementation of reinforced concrete structures 1.NP. The thesis is a proposal for construction site, which is complemented by a social facilities and offices. For an overall view of the construction of a multifunctional complex is processed time and financial plan, which will be further elaborated for building construction B. Availability of supply is verified by the design of routes. Like other task will be processed proposal formwork system for con-struction 1.NP Building B.
Design of Formula Student Front Axle Adjustable Stabilizer
Ševčík, Jan ; Hejtmánek, Petr (referee) ; Porteš, Petr (advisor)
Diploma thesis focuses to design anti roll-bar for Formula Student car Dragon II build in FME. This work follows the proposal anti roll-bar car Dragon I of Jan Krasula. Task of this work is analyses last design, introduce more effective method treatment, create own design with parameters which will be better then last design. An integral part design is prepare manufacture documentation which will be base for manufacture of this komponent
Study of mechanism and kinetics of hexa-1,5-diene polymerisation catalyzed by phenoxy-imine titanium complex and MAO
Ševčík, Jan ; Cihlář, Jaroslav (referee) ; Hermanová, Soňa (advisor)
This diploma thesis is focused on study of polymerization of hexa-1,5-diene catalyzed by phenoxy-imine titanium dichloride (FI Ti) and methylaluminoxane (MAO) as cocatalyst. Effect of monomer concentration, polymerization temperature and cocatalyst/catalyst ratio on catalytic activity, molecular weights, polydispersities and particularly microstructure of prepared poly(hexa-1,5-diene) was studied. 1H NMR spectroscopy revealed that the poly(hexa-1,5-diene) microstructure contained methylene-1,3-cyclopentane (MCP) as well as vinyl tetramethylene (VTM) units. Kinetics of this polymerization was studied. Finally, copolymer of ethene and hexa-1,5-diene possessing incorporated pendant vinyl group was prepared.
Study population of bacteria by image analysis methods
Ševčík, Jan ; Veselá, Mária (referee) ; Zmeškal, Oldřich (advisor)
This bachelor thesis is focused on monitoring and application of image analysis methods on Bacillus megaterium and Cupriavidus necator bacteria. The introduction describes a general knowledge about bacteria, microscopic and image analysis methods. At first it was necessary to prepare suitable microscopic specimens using Gram staining for the observation of a bacteria cell. Every picture of bacteria was taken using a CCD camera and a microscope. Box–Counting method was used to identify the optimal threshold value, corresponding to their fractal measure (or surface areas covered with bacteria) and fractal dimension (or entropy of their arrangement on the surface area). After thresholding, the images were further processed using the Mass–Radius method, which defines a distribution of bacteria relative to the centroid of a cluster.

National Repository of Grey Literature : 26 records found   previous11 - 20next  jump to record:
See also: similar author names
6 Ševčík, Jakub
7 Ševčík, Jaroslav
1 Ševčík, Jiří
2 Ševčík, Josef
1 Ševčík, Julius
1 Ševčík, jiří
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