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The Employment Rate Based on the Present Valid Legal Amendment and Role of the Employment Bureau
VÍTKOVÁ, Ivana
This thesis is based on the current status of unemployment in the Czech Republic, on the current applicable legislation, and it takes into account the latest regulations of the Labor Code and the Employment Act. It also focuses on the work of the employment bureaus, particularly their retraining activities. It also analyzes the issue of so-called illegal employment. The practical part of the thesis covers the situation on the labor market in the Kutná Hora region. We studied the rate of unemployment and its flow in the individual micro-regions. We analyzed the structure of job seekers in terms of education and age. We also focused on the problems of the youth, school graduates, foreigners and handicapped people on the labor market in the area. During the period in question we evaluated the active employment policy of the Kutná Hora employment bureau. Here we performed an analysis of retraining of the job seekers, their placement and success on the labor market. The thesis provides a picture of the employment policy in the Czech Republic, which can be used to acquire comprehensive knowledge of this area.
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The effect of acute cold and permanent light to left ventricular of the rat heart
Vítková, Ivana ; Žurmanová, Jitka (advisor) ; Bendová, Zdeňka (referee)
Acute cold exposure increases the risk of sudden cardiac events, similarly exposure to constant light negatively affects the cardiovascular system. However, the individual effects of these factors and the effect of their combination on cardiomyocytes are not yet known. The thesis deals with the influence of a 3 day cold exposure and constant light on the expression of β-adrenergic receptors and associated G-proteins in association with apoptotic signals in the left ventricle of the Wistar rat heart. In this work apoptotic proteins BAX, BCL2, caspase 8 and important components of β-adrenergic signalization - β1, β2, G-proteins, Gas, Gi1/2 and Gi3 were determined. The relative expression of the proteins was analyzed by Western blotting. The results confirm the detrimental effect of cold and light exposure. However, the synergistic effect of these two stressors shows surprising results.
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The effect of acute cold and permanent light to left ventricular of the rat heart
Vítková, Ivana ; Žurmanová, Jitka (advisor) ; Bendová, Zdeňka (referee)
Acute cold exposure increases the risk of sudden cardiac events, similarly exposure to constant light negatively affects the cardiovascular system. However, the individual effects of these factors and the effect of their combination on cardiomyocytes are not yet known. The thesis deals with the influence of a 3 day cold exposure and constant light on the expression of β-adrenergic receptors and associated G-proteins in association with apoptotic signals in the left ventricle of the Wistar rat heart. In this work apoptotic proteins BAX, BCL2, caspase 8 and important components of β-adrenergic signalization - β1, β2, G-proteins, Gas, Gi1/2 and Gi3 were determined. The relative expression of the proteins was analyzed by Western blotting. The results confirm the detrimental effect of cold and light exposure. However, the synergistic effect of these two stressors shows surprising results.
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