National Repository of Grey Literature 94 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
Detection of pathologies in ECG signals
Němec, Radek ; Mézl, Martin (referee) ; Kašpar, Jakub (advisor)
This thesis attempts with methods for detection of pathologies in ECG signals. The first part is focused on the basic theory of heart anatomy, electrocardiography and individual heart pathologies. The second part describes the preprocessing of ECG signals, detection of QRS complexes and detection of individual pathologies. In the third part the detector is being tested on CSE database and my own measured data.
Evolution algorithms for ultrasound perfusion analysis
Kolářová, Jana ; Odstrčilík, Jan (referee) ; Mézl, Martin (advisor)
This master´s thesis is focused on the application of evolutionary algorithms for interleaving data obtained by ultrasound scanning of tissue. The interleaved curve serves to estimate perfusion parameters, thus allowing to detect possible pathophysiology in the scanned area. The theoretical introduction is devoted to perfusion and its parameters, contrast agents for ultrasonic application, ultrasonic modality scanning, optimization, evolutionary algorithms in general and two selected evolutionary algorithms - genetic algorithm and bee algorithm. These algorithms were tested on noisy data obtained from clinical images of mice with tumor. The final part summarizes the results of the practical part and provides suggestions and recommendations for further possible development.
Comparison of Pharmacokinetic models for DCE-MRI
Bačovská, Kristýna ; Mézl, Martin (referee) ; Jiřík, Radovan (advisor)
This thesis deals with perfusion analysis using DCE-MRI (Dynamic contrast-enhanced magnetic resonance imaging). DCE-MRI is commonly used for microcirculation evaluation mainly in oncology and in recent years also in cardiology. The theoretical overview focuses on the issue of pharmacokinetic modeling and the estimation of perfusion parameters using selected models. The experimental part describes research software PerfLab and then it is aimed at the proposed program for synthetic data generation. Simulated data obtained under ideal conditions and in the presence of noise were used to compare models for the accuracy and reliability of DCE-MRI analysis.
Advanced analysis of signals from gait laboratory.
Húsková, Michaela ; Mézl, Martin (referee) ; Svozilová, Veronika (advisor)
The aim of the thesis is a realization of advanced analysis of signals from gait laboratory. The introductory part deals with the gait cycle and its relation to the joints kinematic is discussed. Additionally, the work is focused on the description of the gait laboratory and the definition of the indexes in order to quantify patient´s overall gait in kinematic analysis. In the practical part, kinematic data analysis was implemented in the MATLAB environment and the results of healthy individuals and patients with cerebral palsy were compared. Kinematic analysis included peak detection in specific kinematic variables. In the last part a graphical user interface for visualization was implemented.
Reduction of metal artifacts in CT data with submicron resolution
Víteček, Jiří ; Mézl, Martin (referee) ; Jakubíček, Roman (advisor)
This diploma thesis deals with reduction of metal artifacts in CT data with submicron resolution. The first part of this thesis briefly describes x-ray computed tomography followed by the description of artifacts of tomographic images and existing approaches of the reduction of metal artifacts. In the second part proposed methods of reduction of metal artifacts and their implementation in Matlab programming environment are described. Finally functionality of algorithms is tested on a newly created database and the results are compared, evaluated and discussed.
Blood vessel segmentation in retinal image data
Vančurová, Johana ; Mézl, Martin (referee) ; Odstrčilík, Jan (advisor)
This master´s thesis deals with blood vessel segmentation in retinal image data. The theoretical part is focused on the basic description of anatomy and physiology of the eye and methods of observing the back of the eye. This thesis also describes the principles of classical and convolutional neural networks and segmentation techniques that are used to segment blood vessel in retinal images. In the practical part, a segmentation method using convolutional neural network U-net is implemented. This neural network is trained on the three datasets. Two datasets include images from experimental video ophthalmoscope. Because it impossible to compare the results of these two datasets with any other methods of retinal blood vessel segmentation, U-net is trained on other dataset that is HRF database. This dataset includes fundus images. The results of testing on this dataset serves for comparing results with other methods of retinal blood vessel segmentation.
3D Model of Cardial Tissue Electrical Propagation
Míková, Monika ; Mézl, Martin (referee) ; Hejč, Jakub (advisor)
The aim of this master thesis is to create a simple 3D electro-anatomical model of cardiac tissue that will be able to simulate the electrical activation in both a healthy heart and a heart with arrhytmogenic substrate. The model of electrical activation is realized in the COMSOL Multiphysics, simulation software for modelling using the finite element method. The Fitzhugh-Nagumo equation was used to model the excitatory feature of the myocardium and 2D models of myocardial tissue describing the propagation of action potential in healthy tissue, ischemic tissue, spontaneous action potential formation in the SA node, and spiral wave formation were first developed based on appropriate parameters. Subsequently, simplified 3D models of the heart describing the spread of excitement in a healthy heart, in the presence of accessory pathway and in third-degree atrioventricular block were created. The simplified 3D heart model offers a compromise between computational load and model complexity and can be used as a diagnostic tool for tissue and whole heart adjustment with appropriate equation parameter settings.
Kinetic analysis of signals from gait laboratory.
Benešovská, Veronika ; Mézl, Martin (referee) ; Svozilová, Veronika (advisor)
Gait analysis has an irreplaceable meaning in many various fields. Thanks to the Vicon system, which is used in gait laboratory, the movement of individual body parts can be captured. The purpose of this work is to process data records from gait laboratory, and kinetic analysis in Matlab program. The main target of the bachelor thesis is to compare detected values, which were evaluated by kinetic analysis of the data obtained from tested subject during performing the exercise and creating GUI.
Systems for acquisition of physiological data during driving
Šimoňáková, Sabína ; Svozilová, Veronika (referee) ; Mézl, Martin (advisor)
The main aim of this bachelor thesis is to compare and evaluate available systems for acquisi-tion of electro physical parameters measured on a driver when driving a car. The main focus is put on reliability, relevance and quality of output signals, that have been measured on participants during a pretest in laboratory and during road testing.
EKG synchonization of electroporation pulses
Nohel, Michal ; Mézl, Martin (referee) ; Novotná, Veronika (advisor)
Bachelor thesis is focused on cells electroporation principle and its types. It further describes thermal and nonthermal ablation techniques with an emphasis on irreversible electroporation. It contains an overview of fields, where medical procedures in combination with ECG signal are used, and an overview of techniques and measurements of the electrocardiographic signal. Further, the sensitivity of the human body to electroporation pulses is discussed. During electroporation, short high-voltage pulses are applied. Ventricular fibrillation may occur if the electroporation pulse is applied to the vulnerable period of the heart rhythm. Synchronization of pulse application with heart activity of the patient is necessary for health and safety reasons in clinical practice. The practical part of the thesis is about a LabVIEW program for this kind of synchronization. The created program is tested and the obtained results achieved are evaluated in terms of practical use.

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