National Repository of Grey Literature 262 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
Microvascular changes in the retina in schizophrenia and depression
Janáčková, Patrícia ; Kudláčková, Zděnka (advisor) ; Herink, Josef (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department: Department of Biological and Medical Science Candidate: Patrícia Janáčková Thesis supervisor: PhDr. Zděnka Kudláčková, Ph.D. Consultant: Prof. MUDr. Ladislav Hosák, Ph.D., Mgr. Veronika Bernhauerová, Ph.D. Thesis Title: Microvascular Changes in the Retina of the Eye in Schizophrenia and Depression Introduction: Mental disorders affect an increasingly large part of the population and negatively affect the quality of life of patients. The course, relapses and therapy of these diseases depend on the early initiation of therapy. Increasing the quality of treatment, diagnosis and assistance for disabled individuals are the main reasons why we started this research. Aim of the work: The main aim of our work was to assess the association between microvascular changes in the retina of the eye and psychological disorders, namely schizophrenia and depression. We also paid attention to demographic and clinical factors that could influence these changes. We were also interested in the etiopathogenesis, treatment and influence of inflammation on schizophrenia and depression, anatomy and vascular supply of the eye or a detailed description of the retina and its pathology. Metodology: The largest part of the research took place at the...
Analysis of perioperative blood loss in hepatopancreatobiliary surgery
Válkyová, Eva Viktória ; Kudláčková, Zděnka (advisor) ; Kovařík, Miroslav (referee)
Author: Eva Viktória Válkyová Department: Department of Biological and Medical Science Name of thesis: Analysis of perioperative blood loss in hepatopancreatobiliary surgery Thesis supervisor: PhDr. Zděnka Kudláčková, Ph.D. Consultants: doc. MUDr.Filip Čečka, Ph.D. ; Mgr. Veronika Bernhauerová, Ph.D. Diploma thesis, Charles University, The faculty of Pharmacy in Hradec Králové Introduction: Hepatopancreatobiliary surgeries are among the most complex surgical procedures and are associated with higher blood loss and postoperative complications. By defining risk factors and optimizing the determination of perioperative blood loss, postoperative complications can be avoided, transfusion administration can be avoided, and the expenses associated with hospitalization of patients can be reduced. Aim of the thesis: The aim of the study was to define the basic anatomical and physiological knowledge of the hapatopancreatobiliary region and to analyze the data set of operated patients with the main focus on their blood loss, transfusions administered and severity of postoperative complications in relation to selected anamnestic parameters. Methods: The analyzed population consisted of patients operated at the Department of Hepatopancreatobiliary Surgery at the University Hospital in Hradec Králové. Patient...
Individualized feeding of premature babies in practice
Kotíková, Aneta ; Hronek, Miloslav (advisor) ; Kudláčková, Zděnka (referee)
The diploma thesis deals with the individualized feeding of preterm infants. The aim of this work was to evaluate the benefits of orofacial stimulation and to compare the values with a group of premature newborns who were fed standardly, without any intervention. The measurement took place in three periods of the child's life. When being discharged from the maternity hospital, in the 1st and 2nd years of life. Evaluation parameters included length of hospitalization, diet at discharge, at 12 and 24 months, and anthropometric parameters such as BMI, weight-height ratio, head circumference, and body length. Orofacial stimulation always took place before each breastfeeding during hospitalization. In the monitored period, statistically significant changes were recorded in the days of hospitalization, diet at discharge, and at 12 and 24 months in preterm infants. Breastfeeding difficulties were significantly reduced after orofacial stimulation. However, the study did not show significant differences in orofacial stimulation on anthropometric parameters. It follows that orofacial stimulation does not affect the growth of the newborn, it only supports and improves the quality of breastfeeding. In summary, it can be said that the orofacial stimulation method is an effective form of breastfeeding support...
Microvascular changes in the retina in schizophrenia and depression
Janáčková, Patrícia ; Kudláčková, Zděnka (advisor) ; Herink, Josef (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department: Department of Biological and Medical Science Candidate: Patrícia Janáčková Thesis supervisor: PhDr. Zděnka Kudláčková, Ph.D. Consultant: Prof. MUDr. Ladislav Hosák, Ph.D., Mgr. Veronika Bernhauerová, Ph.D. Thesis Title: Microvascular Changes in the Retina of the Eye in Schizophrenia and Depression Introduction: Mental disorders affect an increasingly large part of the population and negatively affect the quality of life of patients. The course, relapses and therapy of these diseases depend on the early initiation of therapy. Increasing the quality of treatment, diagnosis and assistance for disabled individuals are the main reasons why we started this research. Aim of the work: The main aim of our work was to assess the association between microvascular changes in the retina of the eye and psychological disorders, namely schizophrenia and depression. We also paid attention to demographic and clinical factors that could influence these changes. We were also interested in the etiopathogenesis, treatment and influence of inflammation on schizophrenia and depression, anatomy and vascular supply of the eye or a detailed description of the retina and its pathology. Metodology: The largest part of the research took place at the...
Measurement of torso muscle volume and its relation to complications in colorectal surgery
Fischerová, Tereza ; Kudláčková, Zděnka (advisor) ; Kovařík, Miroslav (referee)
10 ABSTRACT Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department Department of Biological and Medical Science Candidate Tereza Fischerová Thesis supervisor PhDr. Zděnka Kudláčková, Ph.D. Consultant MUDr. Jiří Kotek Thesis Title Measurement of torso muscle volume and its relation to complications in colorectal surgery Introduction: Colorectal cancer is frequent oncological disease. The primary solution for cure is surgical resection of the tumor, which can be accompanied by a number of complications. The incidence of postoperative complications also depends on the preoperative condition of the patient, such as nutrition and muscle condition. Sarcopenia is a degenerative disease of skeletal muscle and is one of the predictors of postoperative complications. Objective: The aim of the thesis was to retrospectively evaluate the connection between occurrence of postoperative complications and muscle volume on the trunk, which was described by psoas density and psoas muscle index. Methods: On CT images in the area of the 3rd lumbar vertebra (L3), we evaluated psoas density and psoas muscle index. The group consisted of 209 patients who underwent rectal resection at the Surgery Clinic of the Faculty Hospital in Hradec Králové between 2017 and 2021. We assessed the connection between psoas...
Assessment of the intake of vitamins in lactating women
Burešová, Nicole ; Kovařík, Miroslav (advisor) ; Kudláčková, Zděnka (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department: Biological and Medical Sciences Tutor: PharmDr. Miroslav Kovařík, Ph.D. Student: Nicole Burešová Title of thesis: Assessment of vitamin intake in lactating women Background: This theses focus to evaluate vitamins intake of lactating women. A sufficient vitamins intake is very important for both mothers and their infants. The aim of this theses was an assessment of lactating women vitamins intake without and including vitamins supplementation. It was determined whether the intake of individual vitamins changed with the duration of lactation, and then the average intake values were compared with the recommended daily allowances (RDA). Finally, the proportion of women who did not meet the RDA was evaluated. Methods: Data collection for this study took place in 2021-2022. There were eleven lactating women between years of age 29 and 40 involved. These women underwent medical examinations at laboratory four times after the delivery - during L1 lactation period (3-4 weeks after the delivery), L2 period (3 months after the delivery), L3 period (6 months after the delivery) and finally L4 period (9 months after the delivery). During the L1 and L2 periods the questionnaires were submitted by 9 women, during L3 period by 10 women and...
Profile of patiens with pelvic organ prolaps
Šavlová, Lucie ; Kudláčková, Zděnka (advisor) ; Fikrová, Petra (referee)
Charles University in Prague, Faculty of Pharmacy Hradec Králové Department: Departmen of Biological and Medical Sciences Author: Lucie Šavlová Supervisior: PhDr. Zdeňka Kudláčková, Ph.D. Consultant: MUDr. Dominik Habeš, Mg. Veronika Bernhauerová, Ph.D. Title of Thesis: Profile of patients with pelvic organs prolapse Introduction: Up to half of women over the age of 50 suffer from the pelvic organs prolapse. Although not a life-threatening condition, descending in higher stages reduces the patient's quality of life. Around 11 % of women therefore opt for an operative solution. Unfortunately, operations correcting the descent of the pelvic organs are burdened by a relatively large rate of return (recurrence) of the descent. Aim of the thesis: The aim of this work was a retrospective evaluation of the success of pelvic organ descent surgeries, analysis of risk factors leading to recurrence and finding out the subjective satisfaction of patients with the operation depending on whether they suffered from recurrence or not. The operations were performed at the University Hospital in Hradec Králové. These were always procedures associated with the use of polypropylene MESH implanted vaginally. Methods: In the evaluation of the first half of the experimental part, the examined group contained 241 women...
Profile of patiens suffering by vulvovaginal discomfort
Beláková, Nikola ; Kudláčková, Zděnka (advisor) ; Jílek, Petr (referee)
Author: Nikola Beláková Name of the thesis: Profile of patients suffering by vulvovaginal discomfort Diploma thesis Charles University in Prague, The faculty of Pharmacy in Hradec Králové Aim of the thesis: The aim of the thesis was to monitor the profiles of female patients with vulvovaginal discomfort, to define this group of patients in more detail, to compare them with a group of healthy women and to find the influence of individual risk factors. Methods: The observed group of women consisted of 91 patients and 35 healthy women in productive age. Women's health data were provided to us by a specialized clinic of vulvovaginal discomfort at the Obstetrics and Gynaecology Clinic of the University Hospital in Hradec Králové. For statistical evaluation of these data, we used tests from Microsoft Excel: two-sample t-test, Chi-square test and McNemar test. Results: By evaluating the provided data, we did not find statistically significant differences in the area of risk factors such as smoking, use of hormonal contraception, childbirth, allergic diseases and others. Thus, the study shows that it is mostly an idiopathic form of vulvovaginal discomfort. We also focused on the effect of previous treatment, with only therapy containing probiotics being statistically significant. We also found statistical...

National Repository of Grey Literature : 262 records found   1 - 10nextend  jump to record:
Interested in being notified about new results for this query?
Subscribe to the RSS feed.