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In-situ compression test of artificial bone foams in controlled environment using X-Ray micro-computed tomography
Glinz, J. ; Kytýř, Daniel ; Fíla, Tomáš ; Šleichrt, Jan ; Schrempf, A. ; Fürst, D. ; Kastner, J. ; Senck, S.
In this study, we investigated specimens of artificial bone foams, developed by the research group for surgical simulators at the UAS Linz, which are used to mimic the haptic feedback of physiologic and pathologic bone for more realistic surgery training. Specimens with two kinds of mineral filler material as well as different amounts of foaming agent were tested in an environmental in-situ loading stage developed by the ITAM CAS and scanned via X-ray micro-computed tomography. In this in-situ stage, specimens can be immersed in liquid and tested under temperature-controlled conditions. Consequently, a total amount of 12 specimens was subjected to compression loading, half of them immersed in water at 36.5 °C and half in dry condition. Results showed that there is no significant influence of liquid immersion to the compression outcome. However, foams with less amount of foaming agent appeared to have smaller pores resulting in higher compression strength.
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Basic biomechanical characterization of polyurethane based artificial cancellous structures
Šleichrt, Jan ; Kytýř, Daniel ; Pithartová, Kateřina ; Senck, S. ; Fürst, D. ; Schrempf, A.
The main goal of this study is to validate elementary mechanical parameters of a newly designed open-cell foam. The purpouse for investigating artificial material is to approach the properties of the human bone in the case of its adequate replacement. Investigated material can be also used as an artificial bone to train surgical procedures and to improve the skills of the surgeons. Four sets of the foam with different chemical composition were subjected to an uniaxial quasi-static loading to describe basic mechanical behaviour of these samples. Based on these experiments, the stress-strain diagrams were created as a comparative tool including calculation of the effective Young’s modulus. The acquired knowledges will be used as input parameters of a follow-up study aimed at describing the morphology of presented structures and their response to mechanical experiments. A distortion effect of porosity on the results is not considered in this study.
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Výskyt mozkových strukturálních abnormalit (CT, MRI) u pacientů s afektivní poruchou
Fürst, Daniel ; Kopeček, Miloslav (vedoucí práce)
V současné době prožíváme velký rozmach zobrazovacích metod. Neustále se zlepšuje jejich dostupnost, jejich rozlišovací schopnosti i možnosti využití jak ve výzkumu, tak v klinické praxi. Pronikají také do psychiatrie, kde se snaží stejně jako v jiných oborech vnést světlo do etiologie nemocí, přispět k jejich diagnostice a léčbě. Pořizovací náklady jsou nemalé, náklady na provedení jednotlivých vyšetření se liší, mohou tedy zatěžovat veřejné rozpočty různým způsobem, proto je třeba, aby byly stanoveny i správné indikace. Jaký význam mají tyto metody při určení výskytu mozkových strukturálních abnormit u pacientů s afektivní poruchou a jaké důsledky má nález těchto abnormit pro samotné pacienty, je cílem předkládané práce.
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