Národní úložiště šedé literatury Nalezeno 122 záznamů.  předchozí11 - 20dalšíkonec  přejít na záznam: Hledání trvalo 0.03 vteřin. 
May bis-intercalator-peptides influence prion aggregation?
Šebestík, Jaroslav ; Hlaváček, Jan ; Stibor, I.
The synthesis of peptide libraries functionalized with 9-aminoacridines (Acr-NH2) was described as well as an assay based on precipitation of amyloidogenic dye from buffer solution HV monitoring of positional-scanning combinatorial libraries.
Analysis of ionic components including polypeptide and protein allergens in water extracts from the airborne dust samples by capillary isotachophoresis
Sázelová, Petra ; Kašička, Václav ; Koval, Dušan ; Peltre, G.
Water extracts of the dust samples collected in different periods in air-filtration devices in Prague car-traffic tunnels and in Parisian metro station were analyzed both in cationic and anionic capillary isotachophoresis modes.
Variability of the human aggregation response of normal platelets to AVP
Pencheva, N. ; Barth, Tomislav ; Barthová, J. ; Penev, M. ; Mladenova, A.
It was found that the sensitivity and the pattern of AVP-induced aggregation depends on the anticoagulant tested, there is significant difference in the aggregation response to AVP between males and females in citrated PRP and thus the platelet receptors could be a useful model system for testing vascular (V1) receptors for AVP.
Synthesis of the bis-cystinyl fragment 225-232/225'-232' of the human IgGl hinge region
Niederhafner, Petr ; Šafařík, Martin ; Hlaváček, Jan
Hinge peptide was prepared using soluble polyethylene glycol (PEG) as a carrier and Boc strategy. We analyzed the peptide by CD.
Binding sites for oostatic peptides in organs of fly .I.Neobellieria bullata./I..
Nazarov, Elšan ; Holík, Josef ; Tykva, Richard ; Hlaváček, Jan ; Bennettová, Blanka ; Slaninová, Jiřina
Using tritiated peptides Asp-Pro, Tyr-Asp-Pro-Ala, Tyr-Asp-Pro-Ala-Pro binding experiments with homogentates on membrane preparations of ovaries were performed. Very low degree of specific binding was detected.
Fluorescent fragments of oxytocin, vasopressin and dDAVP
Maixnerová, Jana ; Klasová, Lenka ; Barthová, J. ; Barth, Tomislav ; Kašička, Václav
Ornithin derivatives of neurohypophyseal hormone fragments 4-9 were synthesized and labeled by 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD-Cl).
Separation of phosphinic pseudopeptide diastereomers by CZE and RP-HPLC
Koval, Dušan ; Kašička, Václav ; Jiráček, Jiří ; Collinsová, Michaela
Capillary zone electrophoresis (CZE) and reverse phase high-performance liquid chromatography (RP-HPLC) were used for separation of diastereomers of phosphinic pseudopeptides. The migration order in CZE with their elution order in RP-HPLC was compared.
Synthesis of new oxytocin analogues with high antagonistic activity
Fragiadaki, M. ; Bissyris, E. ; Magafa, V. ; Slaninová, Jiřina ; Cordopatis, P.
The synthesis of new OT analogues bearing the following modifications: L-ŕ-t-butylglycine [Gly(Bu')] at positions 8 and 9, D-Cys and D-Tyr(Et) at positions 6 and 2, respectively, and Mpa or Pen at position 1 have been described.
Separation of structurally related peptides by open-tubular capillary electrochromatography using (metallo)porphyrins as the adsorbed stationary phase
Charvátová, Jana ; Kašička, Václav ; Barth, Tomislav ; Deyl, Zdeněk ; Mikšík, Ivan ; Král, V.
Four octapeptides, derivatives of the B23-B30-fragment of the B-chain of human insulin withminor changes in their sequences were studied as model analytes. Separations were performed both in alkaline (pH 9.0) and acidic (pH 2.25) background electrolytes.
Study of neurotoxicity and neuroprotectivity using NG 108-15 cells
Borovičková, Lenka ; Šloncová, Eva ; Slaninová, Jiřina
Factors influencing testing of neuroprotectivity of peptides based on the structure of humanin are described.

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