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Epidemiology of obstructive sleep apnea in patients with Type 2 diabetes - prevalence, screening and adherence to diagnostic proces and the treatment
Westlake, Kateřina ; Polák, Jan (advisor) ; Jirkovská, Alexandra (referee) ; Ludka, Ondřej (referee)
Introduction: Obstructive sleep apnea (OSA) is a condition significantly increasing cardiovascular mortality. In the population of Type 2 diabetes (T2D) patients, OSA is highly prevalent, but mostly undiagnosed. Screening for OSA in T2D patients is still not routine practice and it is also uncertain what the most effective screening method is. The aim of this study was 1) to establish the prevalence of OSA in T2D patients 2) to compare the performance of screening questionnaires and to determine a suitable screening method 3) to find out the adherence of T2D patients to the diagnostic process and OSA treatment 4) to compare adherence to treatment between T2D and regular sleep clinic patients. Methods: 494 consecutive patients with T2D were recruited and asked to fill in screening questionnaires, to undergo screening and, if indicated, diagnostic home sleep monitoring. Those with clinically significant OSA (apnea hypopnea index ≥ 15) were recommended CPAP (continuous positive airway pressure) treatment. Patient follow-up continued for 12 months and their adherence to CPAP was compared to adherence of sleep clinic patients. Results: Clinically significant OSA was found in 94 (31%) out of 294 T2D patients. The sensitivity and the specificity of all three scrutinized questionnaires (Berlin, STOP and...