National Repository of Grey Literature 311 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
Tax Kobra assessment
Bílková, Hana ; Sieber, Martina (advisor) ; Vlček, Josef (referee)
The theme of my bachelor thesis is the evaluation of an investment. More specifically, the investment that I am going to evaluate is a state project of the Czech Republic called Tax Cobra, which is a little bit different in reality than in my thesis. The bachelor thesis is divided into two parts: the first is theoretical, whereas the second is practical. In the first part, I explain what the Tax Cobra is, how and why this project was made, and who the members of it are. I also explain how the investment is evaluated. I summarize the individual methods of investment valuation and other necessary indicators that are important to take into account, such as the cost per capita lor risk. There is also a description of the financial plan. In the practical part, I valuate the project by using the method described in the theoretical part. There is a substantial description of the financial plan, which is crucial for the evaluation. Following this description, I assert the methods of investment evaluation. Ultimately, I would recommend this investment based on these evaluations.
Real world data and health-economics aspects of treatment of respiratory diseases in the Czech Republic
Valena, Tomáš ; Klimeš, Jiří (advisor) ; Vlček, Jiří (referee)
CharlesUniversityinPrague Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate Mgr. TomášValena Supervisor PharmDr. Jiří Klimeš,Ph.D.,MBA Title of RigorosumThesis Real world data and health-economicaspectsoftreatment of respiratory diseasesinthe CzechRepublic The aim of this PharmD thesis was to present comprehensive commentary on author`s publications focusingonthe healtheconomicsaspectsandreal worlddatainthe areaof healthtechnologiesinthe CzechRepublic,specificallyforrespiratorydiseases. The Health Technology Assessment (HTA) is a multidisciplinary evaluation process that assess information on medical, social, economic (cost-effectiveness and budget impact) and ethical aspects relatedtothe use of ahealthtechnologythroughoutitslifespan.Healtheconomicsandevidencefrom real worldare an integral partof HTA. Research focuses on the importance and application of data collection and adaptation of health economic analyses in conditions of local clinical practice in the treatment of respiratory diseases, namely chronic obstructive pulmonary disease (COPD) and severe asthma. This data could be subsequentlyusedasatool for value demonstrationformanagedentryof the drugwhere there isan uncertaintyfromregulatororpayer,whetheronthe side of outcomesorcosts of intervention. The...
The analysis of drug-related problems potentially leading to hospitalization among geriatric patients
Očovská, Zuzana ; Vlček, Jiří (advisor) ; Rozsívalová, Petra (referee)
Candidate: Zuzana Očovská1 Supervisor: prof. RNDr. Jiří Vlček, CSc.1 Consultant: PharmDr. Martina Maříková2 1 Department Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University 2 University Hospital Hradec Králové, Hospital Pharmacy, Head of the Division of Clinical Pharmacy Title of the master thesis: The analysis of drug-related problems potentially leading to hospitalization among geriatric patients Hospital admissions due to drug-related problems (DRPs) represent a relevant clinical issue with significant economic consequences. Polypharmacy and age-related pharmacokinetic and pharmacodynamic changes make elderly patients particularly prone to develop DRP. The aim of the theoretical part of this thesis was to introduce the issue of drug-related problems and to outline the results of previous studies concerning drug-related hospitalizations among geriatric patients. The aim of the practical part was to determine the prevalence of DRP potentially leading to hospitalization and to identify the most common medication classes involved in these DRPs. Over the period of six months 200 admissions to geriatric ward of III. Internal Gerontometabolic Clinic of University Hospital Hradec Králové have been retrospectively evaluated in order to determine whether the...
WorkPprogress Report and Achievements for 2018.
Jirsa, P. ; Vlček, J. ; Veselý, Václav
It was designed by SMS CZ demonstration unit for which basic functional tests have been performed. Operational data and protocols from the basic unit testing are presented. Small modifications of heat exchanger have been proposed. It is expected to propose fuel dosage control with regard to operator level and operation conditions.
WorkPprogress Report and Achievements for 2017.
Jirsa, P. ; Vlček, J. ; Veselý, Václav
On the design process instrumentation diagram, basic drawings of individual elements and parts of the technology were created. One of the main technological nodes was tested - a screw feeder for fuel feeding into the combustion chamber. Combustion tests were carried out on existing pilot combustion technology. The results were used to design and optimize individual nodes to the planned mobile unit prototype.
Hybrid Methods for Nonlinear Least Squares Problems
Lukšan, Ladislav ; Matonoha, Ctirad ; Vlček, Jan
This contribution contains a description and analysis of effective methods for minimization of the nonlinear least squares function F(x) = (1=2)fT (x)f(x), where x ∈ Rn and f ∈ Rm, together with extensive computational tests and comparisons of the introduced methods. All hybrid methods are described in detail and their global convergence is proved in a unified way. Some proofs concerning trust region methods, which are difficult to find in the literature, are also added. In particular, the report contains an analysis of a new simple hybrid method with Jacobian corrections (Section 8) and an investigation of the simple hybrid method for sparse least squares problems proposed previously in [33] (Section 14).
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Application of the Infinitely Many Times Repeated BNS Update and Conjugate Directions to Limited-Memory Optimization Methods
Vlček, Jan ; Lukšan, Ladislav
To improve the performance of the L-BFGS method for large scale unconstrained optimization, repeating of some BFGS updates was proposed. Since this can be time consuming, the extra updates need to be selected carefully. We show that groups of these updates can be repeated infinitely many times under some conditions, without a noticeable increase of the computational time; the limit update is a block BFGS update. It can be obtained by solving of some Lyapunov matrix equation whose order can be decreased by application of vector corrections for conjugacy. Global convergence of the proposed algorithm is established for convex and sufficiently smooth functions. Numerical results indicate the efficiency of the new method.
The clinical application of bioimpedance spectroscopy in polytrauma patients and in pregnant women
Josková, Věra ; Hronek, Miloslav (advisor) ; Vlček, Jiří (referee) ; Kacerovský, Marian (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate: Mgr. Věra Josková Supervisor: doc. PharmDr. Miloslav Hronek, Ph.D. Title of Doctoral Thesis: The clinical application of bioimpedance spectroscopy in polytrauma patients and in pregnant women Introduction and Objectives: Bioimpedance spectroscopy (BIS) is a non-invasive method determining the amount of body fluids and their distribution into the extracellular (ECW) and intracellular (ICW) space, based on the tissue resistance. It has already been applied in many clinical trials in healthy volunteers and in different groups of patients to assess body composition. Furthermore, it seems to be useful in nutritional counseling. However, in critically ill patients hospitalized in intensive care unit (ICU) or in pregnant women, this method has not been used in routine clinical practice as yet. Both of these groups are characterized by the state of increased body fluids. For this reason, BIS could be applied in respective groups of patients. Hence, the main aims of this doctoral thesis were: 1) to describe in detail the principle and the previous use of BIS; 2) to use the BIS to determine the degree of hyperhydratation of patients with polytrauma (PP), and to evaluate the results with the...
Mountain hotel
Vlček, Jan ; Pilný, Ondřej (referee) ; Berková, Petra (advisor)
The aim of this diploma thesis is to design a mountain hotel in the village Rokytnice nad Jizernou. The object is placed on a sloping plot located in an attractive touristic and skiing area of mountain range Krkonoše. The mountain hotel has 4 floors and a basement. In the First floor there is a restaurant with a terrace, kitchen and administrative facilities of hotel. In the second and third floor we can find guest rooms and room for the hotel staff. In the basement there is wellness, technical facilities and garage compound. Construction of building is made of the reinforced concrete monolithic transverse frames with beam filling of ceramic block.
Final report of the project - Secure erasing memory chips using electromagnetic pulse
Fitl, Přemysl ; Vrňata, M. ; Fišer, L. ; Novotný, Michal ; Scholtz, V. ; Vlček, J. ; Tomeček, D.
The subject of this contractual research was the theoretical analysis and the mathematical model of the problem of electromagnetic pulse penetration and involvement of storage function of the memory chips. The report includes description of the experimental preparation memory chip, methodology of memory media testing, experiment shielding, software scanning of the memory chip, EMP generation, EMP intensity measurement. \nSummary of results of experiments of EMP influence on the memory media.\nA comprehensive research report was handed over to NUKIB representatives on 31 May 2018. NUKIB representatives confirmed receipt of the report. \nDefense of the project results took place on 27.6.2018 in the NUKIB building. Project goals were fulfilled. The agreed amount was invoiced for this report.\n\n

National Repository of Grey Literature : 311 records found   1 - 10nextend  jump to record:
See also: similar author names
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8 Vlček, Jakub
37 Vlček, Jan
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2 Vlček, Jozef
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