National Repository of Grey Literature 316 records found  1 - 10nextend  jump to record: Search took 0.04 seconds. 
Unconditional basic income as a solution to unemployment
Hron, Matouš ; Mazák, Jaromír (advisor) ; Vlček, Josef (referee)
In this bachelor thesis I seek an answer to a question whether universal basic income can serve as a solution to mass unemployment. I use theories that explain the causes of reduced well-being of the unemployed. According to restricted agency model, the reduced well-being can be explained by material deprivation. Latent deprivation model seeks the answer in non-material needs that are not fulfilled in unemployment. In the first part of the thesis, I make use of empirical studies of unemployment, whereas in the second part I seek the answer by analyzing European Social Survey data from Czech Republic using multiple linear regression method. In case of evidence supporting the restricted agency model, universal basic income might be a viable solution to unemployment. The results show mixed evidence for both models.
Nucleation in complex systems
Kulveit, Jan ; Demo, Pavel (advisor) ; Slanina, František (referee) ; Vlček, Jaroslav (referee)
Title: Nucleation in complex systems Author: Jan Kulveit Institute: Institute of Physics of the Czech Academy of Sciences Supervisor: prof. Pavel Demo, Institute of Physics of the Czech Academy ofSciences, Department of Optical Materials Abstract: We studied nucleation in progressively more abstract contexts and systems, starting from classical nucleation theory and ending with nucleation in complex networks. The cases studied include impurity nucleation in a solid matrix on several alkali halide crystals, where we determined formation energies for clusters, treated as defects, starting from single impurity-vacancy dipole and small aggregates to possible configurations of larger clusters. In the next part, we turn to the study of heterogeneous nucleation. While in the usual treatment of heterogeneous nucleation the surface energy is assumed to be homogenous, we ask the question what happens if we consider the surface energy to be heteroge- neous.Utilizing umbrella sampling computer simulations we find the nucleation barrier can be significantly lowered in the presence of surface heterogeneity, even if the average surface energy is kept constant. In the last part we study influence of clustering coefficient on phase transitions in scale-free networks, using forward flux sampling (FFS). Keywords: nucleation,...
Analysis of drug problems at hospital department from the pharmacist's point of view
Dvořáčková, Eliška ; Vlček, Jiří (advisor) ; Trejtnar, František (referee) ; Urbánek, Karel (referee)
práce v anglickém jazyce Title: Analysis of drug problems at hospital department from the pharmacist's point of view Introduction: Chronic kidney disease is a medical and economic problem. It affects 10-13 % of the population in European countries and incidence is increasing with every decade of life. The most common cause of kidney failure in patients over 50 years of age is associated with 2. type diabetes and hypertension. Chronic kidney disease is associated with risk of mortality, hospitalization and decreased quality of life. Clinical pharmacist as a specialist in a field of pharmacotherapy collaborates with other health professionals to optimize pharmacotherapy. Proactive approach with active prevention of drug related problems (DRPs) is preferre. Identification and minimization of drug problems together with optimization of pharmacotherapy are the main objectives of clinical pharmacy. Where the prerequisite for the detection and resolution of drug problems is not only knowledge of pharmacology but also other medical disciplines such as biochemistry, microbiology, pathophysiology and epidemiology. This work is one of the first publications of this type in the Czech Republic, which reveals a review of pharmacotherapy in patients with chronic kidney disease and the integration of a pharmacist...
The influence of pulse glucocorticoid therapy on ECG
Juríková, Nikola ; Vlček, Jiří (advisor) ; Rozsívalová, Petra (referee)
Candidate: Nikola Juríková1 Supervisor: prof. RNDr. Jiří Vlček, CSc.1 Consultant: doc. MUDr. Tomáš Soukup, PhD.2 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University 2 2nd Department of Internal Medicine - Gastroenterology, University Hospital in Hradec Králové Title of the master thesis: Effect of pulse glucocorticoid therapy on ECG Glucocorticoid pulse therapy (PT) is used to terminate acute exacerbations of immunologically mediated diseases. The aim of this thesis was to analyze the influence of methylprednisolone (MP) PT on ECG changes, mainly on QT interval, as prolonged QT interval may induce ventricular arrhythmias and to identify other risk factors (RF) for QT prolongation. Data were gained retrospectively from medical records of patients hospitalized at II. Internal Gastroenterology Clinic of University Hospital Hradec Králové. QT was corrected to QTc using Bazzet (QTcB) and Fridericia (QTcF) formula, QTc >450 ms (men) and QTc >460 ms (women) was considered prolonged. QTc changes before and after pulse therapy were determined as ∆QTc. 325 pulses of MP were administered to 277 patients (66,0 % women), ECG was available in 94,2 % (n=306 from 325). After PT there was significant ∆QTcF 14,6 ms (p <0,001) and ∆QTcB 5,6 ms (p <0,001)....
Analysis of non-cardiac adverse event of glucocorticoid pulse therapy
Polláková, Lenka ; Vlček, Jiří (advisor) ; Macek, Karel (referee)
5 ABSTRACT Candidate: Lenka Polláková1 Supervisor: prof. RNDr. Jiří Vlček, CSc.1 Consultant: doc. MUDr. Tomáš Soukup, Ph.D.2 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University 2 2nd Department of Internal Gastroenterology, University Hospital in Hradec Králové Title of the master thesis: Analysis of non-cardiac adverse event of glucocorticoid pulse therapy Intravenous glucocorticoid pulse therapy (PT GC) is effective in life threatening flares of rheumatic diseases. However, due to GC's pleiotropic effect, higher doses and additive nongenomic mechanism in pulse regimen, it is not free of complications (1). The aim of theoretical part was to describe from literature research the relevance of PT GC, its non- cardiac adverse events (AE) in rheumatic patients and their influencing factors. The aim of experimental part of the study was to analyze the occurrence of non-cardiac AE in real-life setting, analyze risk factors of potential adverse drug reactions (ADR) and its complications and analyze the risk minimalization management in real-life setting. Patients were administered 1000 mg methylprednisolone in 3 to 5 doses on alternating days. Analysis includes 277 rheumatic patients with 325 pulse therapy courses. Data were collected retrospectively from their...
Tax Kobra assessment
Bílková, Hana ; Sieber, Martina (advisor) ; Vlček, Josef (referee)
The theme of my bachelor thesis is the evaluation of an investment. More specifically, the investment that I am going to evaluate is a state project of the Czech Republic called Tax Cobra, which is a little bit different in reality than in my thesis. The bachelor thesis is divided into two parts: the first is theoretical, whereas the second is practical. In the first part, I explain what the Tax Cobra is, how and why this project was made, and who the members of it are. I also explain how the investment is evaluated. I summarize the individual methods of investment valuation and other necessary indicators that are important to take into account, such as the cost per capita lor risk. There is also a description of the financial plan. In the practical part, I valuate the project by using the method described in the theoretical part. There is a substantial description of the financial plan, which is crucial for the evaluation. Following this description, I assert the methods of investment evaluation. Ultimately, I would recommend this investment based on these evaluations.
Real world data and health-economics aspects of treatment of respiratory diseases in the Czech Republic
Valena, Tomáš ; Klimeš, Jiří (advisor) ; Vlček, Jiří (referee)
CharlesUniversityinPrague Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate Mgr. TomášValena Supervisor PharmDr. Jiří Klimeš,Ph.D.,MBA Title of RigorosumThesis Real world data and health-economicaspectsoftreatment of respiratory diseasesinthe CzechRepublic The aim of this PharmD thesis was to present comprehensive commentary on author`s publications focusingonthe healtheconomicsaspectsandreal worlddatainthe areaof healthtechnologiesinthe CzechRepublic,specificallyforrespiratorydiseases. The Health Technology Assessment (HTA) is a multidisciplinary evaluation process that assess information on medical, social, economic (cost-effectiveness and budget impact) and ethical aspects relatedtothe use of ahealthtechnologythroughoutitslifespan.Healtheconomicsandevidencefrom real worldare an integral partof HTA. Research focuses on the importance and application of data collection and adaptation of health economic analyses in conditions of local clinical practice in the treatment of respiratory diseases, namely chronic obstructive pulmonary disease (COPD) and severe asthma. This data could be subsequentlyusedasatool for value demonstrationformanagedentryof the drugwhere there isan uncertaintyfromregulatororpayer,whetheronthe side of outcomesorcosts of intervention. The...
The analysis of drug-related problems potentially leading to hospitalization among geriatric patients
Očovská, Zuzana ; Vlček, Jiří (advisor) ; Rozsívalová, Petra (referee)
Candidate: Zuzana Očovská1 Supervisor: prof. RNDr. Jiří Vlček, CSc.1 Consultant: PharmDr. Martina Maříková2 1 Department Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University 2 University Hospital Hradec Králové, Hospital Pharmacy, Head of the Division of Clinical Pharmacy Title of the master thesis: The analysis of drug-related problems potentially leading to hospitalization among geriatric patients Hospital admissions due to drug-related problems (DRPs) represent a relevant clinical issue with significant economic consequences. Polypharmacy and age-related pharmacokinetic and pharmacodynamic changes make elderly patients particularly prone to develop DRP. The aim of the theoretical part of this thesis was to introduce the issue of drug-related problems and to outline the results of previous studies concerning drug-related hospitalizations among geriatric patients. The aim of the practical part was to determine the prevalence of DRP potentially leading to hospitalization and to identify the most common medication classes involved in these DRPs. Over the period of six months 200 admissions to geriatric ward of III. Internal Gerontometabolic Clinic of University Hospital Hradec Králové have been retrospectively evaluated in order to determine whether the...
WorkPprogress Report and Achievements for 2018.
Jirsa, P. ; Vlček, J. ; Veselý, Václav
It was designed by SMS CZ demonstration unit for which basic functional tests have been performed. Operational data and protocols from the basic unit testing are presented. Small modifications of heat exchanger have been proposed. It is expected to propose fuel dosage control with regard to operator level and operation conditions.
WorkPprogress Report and Achievements for 2017.
Jirsa, P. ; Vlček, J. ; Veselý, Václav
On the design process instrumentation diagram, basic drawings of individual elements and parts of the technology were created. One of the main technological nodes was tested - a screw feeder for fuel feeding into the combustion chamber. Combustion tests were carried out on existing pilot combustion technology. The results were used to design and optimize individual nodes to the planned mobile unit prototype.

National Repository of Grey Literature : 316 records found   1 - 10nextend  jump to record:
See also: similar author names
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11 VLČEK, Jiří
8 Vlček, Jakub
37 Vlček, Jan
11 Vlček, Jiří
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2 Vlček, Jozef
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