National Repository of Grey Literature 5 records found  Search took 0.00 seconds. 
Analysis of novel members of FAHFA lipid class derived from omega 3-PUFA by LC-MS/MS and LC-MS/MS/MS
Rombaldová, Martina ; Kuda, Ondřej ; Březinová, Marie ; Slavíková, Barbora ; Pošta, Martin ; Beier, Petr ; Janovská, Petra ; Veleba, J. ; Kopecký Jr., J. ; Kudová, Eva ; Pelikánová, T. ; Kopecký, Jan
White adipose tissue (WAT) is a complex organ with both metabolic and endocrine functions. Dysregulation of all of these functions of WAT, together with low-grade inflammation of the tissue in obesity, contributes to the development of insulin resistance and type 2 diabetes. Omega-3 polyunsaturated fatty acids (PUFA) of marine origin play an important role in resolution of inflammation and exert beneficial metabolic effects. Using LC-MS/MS method, we elucidated the structures of novel members of fatty acid esters of hydroxy fatty acids (FAHFA), which were present in murine and human serum and WAT after omega-3 PUFA supplementation in diet. These compounds contained DHA esterified to 9- and 13-hydroxyoctadecadienoic acid (HLA) termed 9-DHAHLA and 13-DHAHLA, and were synthesized in WAT. Our results document the existence of novel lipid mediators, which are involved in the beneficial anti-inflammatory effects attributed toomega-3 PUFA, in both miceandhumans.
Detection of ventricular extrasystoles
Veleba, Josef ; Vítek, Martin (referee) ; Mézl, Martin (advisor)
This thesis focuses on the issue of ventricular extrasystoles and their detection in ECG signal. It provides a brief description of physiological electrical activity of the heart with the theoretical analysis of ventricular extrasystoles, QRS complex detection methods and the related detection of premature ventricular contractions. The main part of the work presents the process of implementation of selected QRS complex detection and premature ventricular contractions detection methods in MATLAB with the evaluation of test results.
Accuracy of methods for detection of atrial fibrillation in ECG signals
Veleba, Josef ; Janoušek, Oto (referee) ; Provazník, Ivo (advisor)
This thesis focuses on the issue of atrial fibrillation and the success of their detection in the ECG signal. It provides a description of electrical activity of the heart with the theoretical analysis of atrial fibrillation and methods for their detection. Additionally the work describes procedures for the implementation of three selected methods for the detection of atrial fibrillation in the MATLAB environment, presents the results of their tests on two atrial fibrillation signal databases and assesses the accuracy of each method.
Prison in Moravské Budějovice
Veleba, Jakub ; Mizerová,, Lenka (referee) ; Petříček, Tomáš (advisor)
Theme of this diploma thesis is a newly buil building of prison in Moravské Budějovice. The buiding has four ground floors and is without cellar. The structural system of the building is made up of permanent formwork and system Porotherm. Ceiling construction is made up of reinforced hollow core slab. The building is covered with a flat roof. family house
Veleba, Jakub ; Jelínek, Petr (referee) ; Sedlák, Jiří (advisor)
This bachelor´s thesis focuses on the development of documentaion of documentaion of a low energy family house in Jemnice. The project as well as the addenda are elaborated with regard to contemporary legislature and standarts. The family house is located on plot number 1152/6 in Jemnice area. The house has two floors. Dimensions of the house are 9,85x12,65m. The roof of the building is designed pitched roof. The house is performed from the system Porotherm. The basic construction are of plain concrete and the base concrete slab. The enclosed essay deals with pitched roofs.

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2 Veleba, Jakub
2 Veleba, Josef
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