National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Early Volumetry of Brain Metastases Treated with CyberKnife
Reguli, Štefan ; Řehák, Svatopluk (advisor) ; Jančálek, Radim (referee) ; Kalita, Ondřej (referee)
The CyberKnife is a device for frameless whole-body radiosurgery using image guided robotic technology and linear accelerator as a photon source. It was introduced in USA in 2001. First CyberKnife device in eastern ad middle Europe was installed in Faculty hospital Ostrava in 2010. So we were given a chance do use the most recent technology in treating oncological patients. Brain metastases are an important and frequently treated indication in modern radiosurgery. This non-invasive method offers good local control with minimum toxicity and repeability of the treatment. Biological aspect and dose delivery is equivalent to devices using framed stereotaxis and cobalt as radiation source (Gamma Knife). The difference is in technological performance. The ability of fraccionated therapy with CyberKnife enables radiotherapy of larger tumours. Patients treated with CyberKnife for metastatic brain disease are checked with repeated magnetic resonance imaging (MRI) to to figure out the growth of treated tumours and/or apperance of new lesions. In our prospective study we measure the volume of brain metastases on MRI with use of computer -assisted volumetry. We evaluate the predictive value of volumetric changes on MRI exams 6 weeks and 12 weeks post radiosurgery respectively. The aim was to identify high-risk...

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