National Repository of Grey Literature 18 records found  1 - 10next  jump to record: Search took 0.00 seconds. 
The role of autophagy in neurodegenerative processes
Marková, Veronika ; Novotný, Jiří (advisor) ; Čermák, Vladimír (referee)
The characteristics of many neurodegenerative diseases including Alzheimer's, Parkinson's and Huntington's disease is the accumulation of proteins and damaged organelles in the cytoplasm. Unfortunately, they are not sufficiently eliminated by autophagy. The basal autophagy, that maintains the cellular homeostasis, is disturbed in neurodegeneration. The process of autophagy becomes saturated and unable to remove all the toxic substances. Therefore, other degradation mechanisms are activated, aiming to restore the homeostasis. However, the neuronal cells are damaged under certain conditions leading to their death. The reduction in the number of neurons in specific brain areas may cause severe ataxias and dementias. Better understanding of autophagocytosis and its role v pathogenesis of neurodegenerative diseases may contribute to more effective treatment of these serious diseases in the future. Key words: autophagy, neurodegeneration, Alzheimer's disease, Parkinson's disease, Huntington's disease
Comparison of Infant Groups and Kindergartens
MARKOVÁ, Veronika
This bachelor thesis is comparing infant groups and kindergardens. The Theoretical part of this thesis deals with the meaning of preschool education, its formation and the development of preschool facilities while focusing on the care of children attending preschool education at infant groups or kindergartens. It describes differences in alimentation, number and age of children attending, educational programs within as well as hygiene requirements for space and service of those facilities. The goal of this thesis was to compare hygiene requirements for space and service and conditions for educational activities at infant groups or kindergarten. For research part, I used quality research with observation and half structured interview. The researchers group contained two infant groups and three kindergartens of South Bohemian region. Those facilities were chosen randomly. Total of five interviews were conducted. Obtained data were divided into categories and for each category two mind maps were made - one of these maps shows answers from kindergarten and the other one answers from infant's groups. Each of those maps was later described. In the research, I looked for differences in alimentation of infant's groups and kindergartens. One of the differences is that infant groups are not required to provide alimentation services. This obligation is than transferred to the parents, who then has to bring food from home to the facility. Another fact is that educational program is not required at infant's groups. I found out from research, when there is education, number of kids and their age don't project on the educational activity. The assumption was that alleviation of hygienic conditions for rooms of daily stay, outside area and hygienic facility of infant groups will show during the operation. This has not ben confirmed by the research. The alleviation of hygienoc conditions, on the contrary, is not apparent and it is due to the fact that there are less childeen in an infant group and they are of considerably youger age than kids in a kindergarten.
Teachers point of view on premature baby in kindergarten
MARKOVÁ, Veronika
This bachelor thesis is focusing particularly on matters regarding prematurity of preschool children. The purpose is to find out how kindergartens teachers perceive it and what problem areas develop in children born prematurely. The thesis is divided into two sections theoretical and empirical. Theoretical part describes prematurity from early age to preschool age of the children. Further on it examines possible consequences of prematurity in postnatal development and systems which take care of these children. Results from research carried out by using qualitative methods are presented in the empiric section of the thesis.
Evaluation of psychical load on a selected workplace
MARKOVÁ, Veronika
In recent years, the interest in mental strain has increased, mainly due to the increasing demands of the individual professions. The consequences of mental strain can also influence private life, so it is important to solve such situation. The diploma thesis deals with the psychological burden of the employees in a private company that produces CNC machine parts. The aim was to find out what the level of mental strain on all employees of the company is, using the method of quantitative and qualitative research. Three research questions have been identified. I have examined whether the demographic factors of the worker, the physical factors in the working environment and the way of rest after work affect the psychological burden. The investigation was carried out using three hypotheses. I assumed that a significant level of psychological burden would be present in relation to the age and that it would also vary by gender. I also expected that the differences in the level of psychological burden would be present depending on the length of the years worked in the company. A qualitative survey was conducted using sixteen open questions in a semi-structured interview. The results were divided into eleven categories and there was a mind map created for each of them. For better understanding of the mind maps, the data was extended by quantitative questionnaire research, which was implemented using standardized CBI questionnaires (Copenhagen Burnout Inventory) and the Meister questionnaire. Questionnaire survey was carried out at each workplace of the surveyed company. The data were processed statistically and graphically. Mixed research has not shown a significant level of mental strain on company employees. When compared the ratio of mental strain in relation to gender, it has shown that the strain on both men and women is the same. The length of employment in the company has not reflected into increased rates of mental strain.
Damages under the United Nations Convention on Contracts for the International Sale of Goods
Marková, Veronika ; Pfeiffer, Magdalena (advisor) ; Brodec, Jan (referee)
The subject of the rigorosum thesis is damages under the United Nations Convention on Contracts for the International Sale of Goods (hereinafter the "CISG"). The CISG can be described as one of the most important and most widely used legislative instruments providing a unified framework for contracts for the international sale of goods. The aim of this thesis is to make a critical analysis of the provisions concerning the right to damages, to confront misleading provisions and to clarify issues not expressly dealt with by the CISG in order to provide a comprehensive overview of the right to damages under the CISG, taking into account its core values and principles. The significance of the CISG in the business world and the purpose of the right to damages are introduced in the first part of the thesis. The CISG is fundamentally influenced by the UNIDROIT Principles1 and PECL2 , which help to interpret vague languages found in the provision and to supplement and to clarify the provisions of the to the CISG. The crucial goal of the right to damages, which is to place the aggrieved party in the same position it would have been in economically if the contract had been performed, is embodied in the principle of full compensation. The goal of the subsequent chapter is to describe all requirements for...
Educational and counseling center Open garden NGOs in Brno - construction technology project
Marková, Veronika ; Nečasová, Barbora (referee) ; Venkrbec, Václav (advisor)
The subject of the diploma thesis is solving of the construction project of the administrative building "Educational and consulting center Open Garden of NGO in Brno" The building is designed as three-storey reinforced concrete skeleton with a flat vegetation roof and a light cladding. The diploma thesis includes technological prescriptions for the assembly of the light cladding and for window installation, inspection and quality plans, design of machine assembly, site equipment project, item budget, etc.
How Smart will be Europe 2020? A Panel Data Analysis.
Marková, Veronika ; Cahlík, Tomáš (advisor) ; Moravcová, Michala (referee)
This thesis analyses the targets for education under Europe 2020 strategy - early leavers from education and tertiary education attainment. The main objective is to predict the future development for these indicators up to 2020 and answer the question whether these targets will be fulfilled. From the empirical perspective, it applies econometric analysis of panel data based on human capital theory, that relates the education level of an individual with the parental education and the labour market conditions.
Meaning and development of traffic information and its specifies
Marková, Veronika ; Trampota, Tomáš (advisor) ; Jirků, Jan (referee)
Diploma thesis "Meaning and development of traffic information and its specifics " deals with function of media, interactivity, news genres and traffic information as a necessary part of nowadays society. It also looks at the media and their meaning in the process of distributing traffic information. The diploma thesis also charts the behaviour of subjects, that are professionally dealing with traffic information. It focuses on news systems and individual broadcasting, that are distributing information about traffic. It also evaluates process of distributing traffic information as a welfare service. The thesis prove that such information are helpful to the public. Timely inteligence and realistic information may help not just the individual drivers, but also to the society as the whole, to the environment and the economy of companies as well. The diploma thesis denotes the beginning of first local system, that collects, processes, distributes and keeps traffic news - Integrated system of traffic information, these information are available for everybody, who applies for them, service is free of charge. Mainly media use this system. I also try to bring closer some technical inovations in traffic broadcasting, that made milestones in this relatively new discipline of mass communication.
Character and significance of discovery voyages in the era of Elizabeth I
Marková, Veronika ; Kovář, Martin (referee) ; Skřivan, Aleš (advisor)
The English Queen Elizabeth I supported naval exploration. English voyages overseas differed in character according to their destinations. At first, voyages northward had been pure voyages of discovery aimed at finding a northwest passage. Only later on, they also became voyages of colonization. The closer the English colonists approached Florida, which was under Spanish rule, the more danger they faced. Voyages southward had always been voyages of piracy as South America belonged to the Portuguese and Spanish spheres of influence. The character of English naval voyages was also determined by the geographical location of the British Isles. For the English, finding a northwest or a northeast passage would have been very profitable. In the forty years of the reign of Elizabeth I, England evolved into a naval power that could challenge Spanish and Portuguese domination in the New World.
Agritourism focusing on South Bohemian Region
Marková, Veronika ; Navrátilová, Miroslava (advisor) ; Toth, Štefan (referee)
The theme of the bachelor thesis is agri-tourism as regards of business opportunities for privately employed farmers. The theoretical part presents the views of experts on tourism and their assessment of business conditions in the area. Work conceives the issue from a broader perspective so. Rural tourism, which is still in our tradition. Its development after the Second World War stopped on time, so then in the sixties and seventies, people again this tradition continue in its own way. In those years the city's population began to buy and renovate rural houses and with it also certainly change the character of rural communities. Popularity rural tourism illustrate the results of the survey, which is the content of the practical part. Respondentskou second group are farmers operating in tourism and agro-tourism offering to its farmách.Results of interviews with eight farmers frequent reveal the reasons for the slow development of this business, which returns in the evaluation spirit of the subsequent discussion. In cinclusion of work are indicate some possibilities of development of tourism and conditions of its application in the tourism market.

National Repository of Grey Literature : 18 records found   1 - 10next  jump to record:
See also: similar author names
19 MARKOVÁ, Veronika
2 MARKOVÁ, Vladimíra
1 MARKOVÁ, Vladislava
3 Marková, Vendula
3 Marková, Věra
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