National Repository of Grey Literature 5 records found  Search took 0.00 seconds. 
Business Plan Proposal for a Company
Krhut, Jan ; Odložilová, Kateřina (referee) ; Konečná, Zdeňka (advisor)
The bachelor thesisis is a proposal of the business plan for the intention to establish the mobile bar. This specific bar combines elements of fast food and classic bar. The thesis consists of three parts. Theoretical part is based on literary research and the elementary terms are defined here. The analytical part deals with market analysis and its needs, using SLEPT and SWOT analysis. The design part is then the proposal of business plan itself.
The effects of mid-urethral tape on symptoms of overactive bladder
Hensel, Germund ; Košťál, Milan (advisor) ; Huvar, Ivan (referee) ; Krhut, Jan (referee)
Background: Mid-urethral tape implantation is at present a common procedure for stress urinary incontinence. It is greatly successful with a low degree of complications. A large part of patients suffering from stress urinary incontinence has co-existing symptoms of overactive bladder (OAB), which can improve in a certain manner after placing of the mid-urethral tape. Data in literature about risk factors for persistence of OAB symptoms are not unanimous. Objectives: To determine the influence of mid-urethral tape implantation on the different symptoms of OAB, to determine risk factors for persistence of OAB symptoms after mid- urethral tape implantation. Methods: The study included 111 female patients suffering at the same time from stress urinary incontinence and symptoms of OAB. All of them underwent implantation of mid- urethral transobturator tape. Using micturition diary and two specific questionnaires (ICIQ- OAB and ICIQ-OABqol) we compared the intenzity of OAB symptoms before and after tape implantation. To determine risk factors for persistence of OAB symptoms we used univariate logistic regression, followed by multivariate regression analysis for selected factors. Results: All the four symptoms of OAB - urgency, frequency, nocturia and urgency incontinence - improved statistically...
Treatment of neurogenic detrusor overactivity using botulinum toxin A
Šámal, Vladimír ; Morávek, Petr (advisor) ; Zachoval, Roman (referee) ; Krhut, Jan (referee)
2. Summary Treatment of neurogenic detrusor overactivity using botulinum toxin A Introduction: The treatment of neurogenic detrusor overactivity (NDO) is still a serious medical, social and economic problem. Using onabotulinumtoxinA (onaBTA) is the first choice in patients who are refractory to standard anticholinergic therapy or with the occurrence of serious adverse events from this treatment. The standard way of applying onaBTA is intramural injection into the detrusor of the urinary bladder. Aim: To evaluate the effectiveness of the NDO treatment with submucosal applications of onaBTA with regard to the complex mechanism of the action of onaBTA on the urinary bladder. Methods: A randomized, prospective open-label study was performed. The study population consisted of patients with neurogenic detrusor overactivity due to spinal cord injury. A total of 23 patients, in which urinary incontinence persisted due to NDO despite anticholinergic therapy, were included. After randomization, patients were treated with 300 U onaBTA applied in 30 injection sites, sparing bladder trigone. In group A the treatment was carried out using submucosal applications and in group B with intramural application into the detrusor. The length of the study was 12 weeks. Urodynamic examination was performed before and after the...

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