National Repository of Grey Literature 98 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
RSS Reader for iOS
Bogdanchikov, Iaroslav ; Rozman, Jaroslav (referee) ; Hrubý, Martin (advisor)
The aim of this work is to create a mobile application for iOS operating system for easy following, reading and storing/archiving of stories from news sites and blogs accessed through web feeds in RSS format. The application is implemented in Swift programming language. Apple's Core Data application framework was used for data persistence. The work consists of theoretical and practical parts. The theoretical part describes the RSS format and principles of programming an application for iOS operating system. The practical part contains description of design, implementation and testing of the application. The resulting application provides user with a simple instrument to work with RSS channels and stories, and by following the Apple Human Interface Guidelines the application fits naturally in iOS ecosystem.
Chelating Polymers for the Haemochromatosis Treatment
Groborz, Ondřej ; Hrubý, Martin (advisor) ; Kotek, Jan (referee)
5 Chelating Polymers for the Haemochromatosis Treatment Author: Ondřej Groborz Tutor: Mgr. Martin Hrubý, Ph.D., DSc. Advisors: Ing. Kristýna Kolouchová Ing. Pavel Švec Institute of Macromolecular Chemistry, Czech Academy of Sciences Abstract Haemochromatosis is a group of hereditary diseases which are characterised by toxic accumulation of iron in parenchymal organs, leading to organ toxicity and irreversible damage. Currently, there are only a few approved medications for this disease, yet all of them possess severe side effects. Herein, we have proposed a new paradigm for treatment: insoluble polymers with negligible systemic biological availability would form stable complexes with iron ions in the gastrointestinal tract, hence decreasing biological availability of iron. The insolubility of polymers prevents them from being absorbed into the organism in the first place while having no systemic side effects or toxicity. We have prepared polymers with several covalently bound iron-chelating ligands and based on the biological data we selected the most successful chelators for possible future applications. These polymers exhibited negligible resorbability and toxicity, superior in vitro iron chelating activity and their efficacy was proven in an in vivo model. Therefore they could be used as a...
iOS Application for Mapping of Gastronomic Services
Martinů, Michal ; Kočí, Radek (referee) ; Hrubý, Martin (advisor)
This bachelor thesis contains design and implementation of application for iOS operating system. Also, it focuses on the description of current technologies used to create an application and the current state of completed solutions. Design, implementation and testing of the application are made thanks to the aforementioned knowledge. The final application allows users to view nearby gastronomic facilities. Contents of the application is created by the users themselves.
iOS Application for Pokemon's GO Players Community
Pihrt, Patrik ; Kočí, Radek (referee) ; Hrubý, Martin (advisor)
Pokémon Go is one of the most successful mobile game applications ever created. The game is supported on Android and iOS platforms. This bachelor's thesis describes the way of finding out certain type of information from game's screenshot. Those screenshots are inserted to the application by user, datas are calculated and Pokémon's individual value is known and showed. Results are saved and can be seen anytime. The application provides the newest gaming information.
Reactive Programming in iOS Applications
Kříž, Matyáš ; Peringer, Petr (referee) ; Hrubý, Martin (advisor)
iOS development is built on asynchronous calls and parallelism. Keeping the asynchronous code clear and consise becomes increasingly more difficult with the size of an application. Multiple methodologies emerged to combat this problem. One of them is the reactive programming methodology. In my thesis I focused on creating a reactive methodology inspired by the core ReactiveX concepts with a simpler, more streamlined implementation.
Mobile Application for Recording of Compulsive Behavior
Foltýn, Martin ; Janoušek, Vladimír (referee) ; Hrubý, Martin (advisor)
The main goal of this bachelor thesis is to design, implement and test mobile application for iOS platform. It will be used to monitor drug and psychical addiction. The app can help the user to see his progress over time, patterns and triggers of its addictive behavior and guide him to the right direction towards abstinence. It is here to understand the user's problems, motivate and give a helping hand. Important aspects in the development were the study of programming of mobile applications, existing solutions, research of the target group of users, theory of addictology and therapy, design and implementation with understandable user interface, testing of results on real users.
Functional nanodiagnostics for 31-P magnetic resonance imaging: New paradigm for noninvasive imaging agents
Pechrová, Zdislava ; Hrubý, Martin (advisor) ; Kotek, Jan (referee)
The topic of my Master degree thesis is the development of a conceptually new class of contrast agents for the 31P magnetic resonance imaging (31P MRI). These agents are based on nanoparticles of calcium(II) phytate. Phytate (myo-inositol-1,2,3,4,5,6-hexakisphosphate) is largely present in plants, seeds and grains. It is non-biodegradable but nontoxic for animals and human beings and most importantly around 22% of its mass is phosphorus, so it is easily detectable by 31P NMR/MRI. These nanoparticles of Ca(II) phytate were doped with paramagnetic Fe3+ ions which broaden the 31P signal, making the nanoparticles invisible in healthy tissues. In the presence of bacteria producing siderophores (for example in Helicobacter pylori in gastric ulcers), Fe3+ is released from the gel and 31P MRI signal becomes detectable. In vitro simulation of this release was performed with deferroxamine, a compound possessing high affinity to Fe3+ ions forming coloured complex with it exploitable for the UV-VIS evaluation. The Ca(II) phytate can be synthesized in two possible ways. The first way is by direct precipitation of the Ca2+ salt with sodium phytate. The second way is ion exchange of phosphate in the nanoparticles of hydroxyapatite which creates electrostatically stabilized calcium phytate nanoparticles. Both...
Novel hybrid polysaccharide-based polymers for biomedicine
Loukotová, Lenka ; Hrubý, Martin (advisor) ; Sedláková, Zdeňka (referee) ; Poučková, Pavla (referee)
1 Abstract This doctoral thesis is focused on the synthesis and characterization of novel hybrid polysaccharide-based polymers applicable for biomedicine, specifically for a conceptually new bimodal cancer treatment - immunoradiotherapy. For this purpose, polysaccharides β-glucan from Auricularia auricula-judae and κ-carrageenan from Kappaphycus alvarezii, exhibiting immunostimulatory and anticancer activities, were chosen to be grafted with thermoresponsive poly(2-isopropyl-2-oxazoline-co-2-butyl-2-oxazoline)s (POXs) (with different graft lengths and grafting densities) that induced a lower critical solution temperature of the final polymers. The thermoresponsive behavior of resulting polymers was studied with temperature-dependent light scattering methods, fluorescence measurements and also nuclear magnetic spectroscopy to select a polymer material with the most suitable properties for the intended application, aiming at a polymer depot formation after the injection of a polymer solution into the body. The chosen polymer, β-glucan-graft-POX with graft length of 2500 Da, was then modified to bear 1,4,7,10-tetraazacyclododecane-1,4,7,10- tetraacetic acid and a fluorescent dye Dyomics-615 at the graft ends and tested first in vitro to investigate its immunostimulatory properties and also the cellular uptake....
ENERGY MANAGEMENT STRATEGY FOR SUSTAINABLE REGIONAL DEVELOPMENT
Hrubý, Martin ; Korytárová, Jana (referee) ; Kabrhel,, Michal (referee) ; Petráš,, Dušan (referee) ; Hirš, Jiří (advisor)
Energy Management strategy for sustainable regional development has been selected as the topic of my research due to the fact that energy demand alongside with energy dependency have been continuously growing from a long term perspective. Sustainable development is defined by three imperatives – energy efficiency, ecology and security. Review of the current state and analysis of historical trends in Energetics at global and regional level are covered in this research. Results of the Multi-Criteria Decision Analysis introduce a set of implications and recommendations for Energy Management strategy in the Czech Republic.
Twitter Client for Apple TV
Zvara, Marek ; Kočí, Radek (referee) ; Hrubý, Martin (advisor)
This paper describes and analyses the tvOS platform and compares its advantages and disadvantages to the iOS platform. In addition, it offers an overview of the current state of the Twitter API.Based on this knowledge, it provides a description of the design, successful implementation and testing of the application. Twitter client works with basic features such as scrolling the timeline, retweet, like / unlike tweet, or responding to a tweet discussion.

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See also: similar author names
1 Hrubý, Marek
1 Hrubý, Matěj
6 Hrubý, Michal
1 Hrubý, Milan
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