National Repository of Grey Literature 30 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
Advanced Moment-Based Methods for Image Analysis
Höschl, Cyril ; Flusser, Jan (advisor) ; Papakostas, George (referee) ; Jiřík, Radovan (referee)
The Thesis consists of an introduction and four papers that contribute to the research of image moments and moment invariants. The first two papers focus on rectangular decomposition algorithms that rapidly speed up the moment calculations. The other two papers present a design of new moment invariants. We present a comparative study of cutting edge methods for the decomposition of 2D binary images, including original implementations of all the methods. For 3D binary images, finding the optimal decomposition is an NP-complete problem, hence a polynomial-time heuristic needs to be developed. We propose a sub-optimal algorithm that outperforms other state of the art approximations. Additionally, we propose a new form of blur invariants that are derived by means of projection operators in a Fourier domain, which improves mainly the discrimination power of the features. Furthermore, we propose new moment-based features that are tolerant to additive Gaussian image noise and we show by extensive image retrieval experiments that the proposed features are robust and outperform other commonly used methods.
Visualization and testing of team profiles
Höschl, Cyril
The aim of this thesis is to demonstrate methods for visualization and testing team profiles. An individual's profile is a vector of scores representing personality of a team member. Team profile is a collection of individual profiles. The first step for visualization of team profile is to find similarities among individual profiles. We present new approach for measuring similarity between two profiles as a significance of difference expressed by probability. We use this measure both for testing mean difference between two subgroups of profiles and also for building similarity matrix. We represent team profiles as a 3D ladscape map called Sociomap. To create a sociomap we demonstrate own algorithm for projecting similarity matrix into a 2D plane. We compare this algorithm with well known Multidimensional scaling and Principal Component Analysis methods solving the same task. Comparing with MDS and PCA, our algorithm provides more accurate result with comparable demand of time. We also employ some well known Computer Graphics methods to improve visual 3D representation of the sociomap and we also show some new improvements to render sociomap more realistic.
New Neurophysiological Indicators Measuring, Monitoring and Evaluating in Selected Psychiatric Disorders
Šóš, Peter ; Höschl, Cyril (advisor) ; Libiger, Jan (referee) ; Hájek, Milan (referee)
There is increasing amount of new knowledge in neuropsychiatric research, partially as a result of application of new neurophysiological methods of quantitative electroencephalography. This is because these techniques have good temporal resolution, are relatively non-invasive and economical. Different experimental paradigms and electroencephalographical analytical techniques are reviewed, with their potential applications in the assessment of psychiatric disorders. In the theoretical part the principles of some methods of quantitative electroencephalography, especially are described: EEG coherences, QEEG cordance and LORETA. Next chapter contains basic information about panic disorder and major depressive disorder followed by findings in functional imaging studies which are associated with the selected psychiatric disorders. Separate section is devoted to the prediction of antidepressant response. The empirical part of the thesis consists of a set of the five original papers about application of QEEG methods in a population of psychiatric patients (Bareš et al., 2010; Kopeček et al., 2008; Kopřivová et al., 2009; Šóš et al., 2008; Šóš et al., 2013). In Study 1, we followed the localization of EEG sources by means of brain electromagnetic tomography with low resolution (LORETA) in patients with panic...
Bipolar Disorder and Diabetes Mellitus
Růžičková, Martina ; Höschl, Cyril (advisor) ; Haluzík, Martin (referee) ; Papežová, Hana (referee)
Despite lots of research, the genetic and pathophysiological basis of bipolar disorder (BD) remains unclear. One of the possible reasons is that BD spectrum comprises a heterogeneous group of different subtypes of the illness sharing certain pathophysiological or genetic mechanisms. Patients with co-morbid diabetes mellitus (DM) may represent such a subgroup of BD with a distinct pathophysiology and possibly different clinical characteristics of BD. This thesis is aimed at investigating the possible link between BD and DM. Bipolar patients have about 3 times higher risk of DM (type 2 in particular). The first part of my thesis outlines the possible links between DM and BD, including medication, alterations in the hypothalamo-pituitary axis and signal transduction, and genetics. In the second part, I examined the possible differences in clinical characteristics between patients with (N=26) and without (N=196) co-morbid DM. Next, I examined the variables showing differences between groups, using logistic regression. Patients were recruited via The Maritime Bipolar Registry. The prevalence of DM was 11.7%. Diabetic patients were significantly older than non-diabetic patients (P < 0.001), had higher rates of rapid cycling (P = 0.02), more chronic course of BD (P = 0.006), more disability (P < 0.001), lower...
Assesment of stress and psychotropic induced changes of trimetric G protein subunit levels and cellular functions in vitro and in vivo in the context of depressive disorder
Páv, Marek ; Kovářů, Hana (advisor) ; Höschl, Cyril (referee) ; Doležal, Vladimír (referee)
Depression is a complex systemic disorder with exhibiting biological, cognitive and psychopathological symptoms. There are changes in hormonal regulation, immune changes and disturbance in function of especially monoamine and indoleamine neurotransmitter circuits in the CNS. Pharmacologic intervention with antidepressants is treating depressive syndrome as well as homeostatic imbalance. These neurotransmitter systems use in the signal transduction from membrane into the cell receptors coupled with heterotrimeric G proteins (GTP binding proteins).This thesis studies changes in G protein subunit levels induced by stress and psychotropic drugs in the CNS and immune system of experimental mice and antidepressant induced changes in vitro in the C6 glioma cell line an in vivo in the rat tissue. Immobilization stress induces prominent changes in the G protein subunit levels in the spleen and CNS of experimental mice with analogical profile of response. Results show importance of stress dopaminergic component in the leukocyte function regulation and also demonstrate importance of dopaminergic regulation without stress exposition. Findings obtained in the glioma C6 cell line show antidepressant induced drug specific changes of the G subunit profiles and demonstrate thus mode of action independent on the...
Visualization and testing of team profiles
Höschl, Cyril ; Mráz, František (advisor) ; Holan, Tomáš (referee)
The aim of this thesis is to demonstrate methods for visualization and testing team profiles. An individual's profile is a vector of scores representing personality of a team member. Team profile is a collection of individual profiles. The first step for visualization of team profile is to find similarities among individual profiles. We present new approach for measuring similarity between two profiles as a significance of difference expressed by probability. We use this measure both for testing mean difference between two subgroups of profiles and also for building similarity matrix. We represent team profiles as a 3D ladscape map called Sociomap. To create a sociomap we demonstrate own algorithm for projecting similarity matrix into a 2D plane. We compare this algorithm with well known Multidimensional scaling and Principal Component Analysis methods solving the same task. Comparing with MDS and PCA, our algorithm provides more accurate result with comparable demand of time. We also employ some well known Computer Graphics methods to improve visual 3D representation of the sociomap and we also show some new improvements to render sociomap more realistic.
Development of photic entrainment of the circadian clock of the rat during early postnatal ontogenesis
Matějů, Kristýna ; Sumová, Alena (advisor) ; Höschl, Cyril (referee) ; Langmeier, Miloš (referee) ; Nevšímalová, Soňa (referee)
In most organisms, behavioral and physiological events oscillate with period ± 24 h, i.e. exhibit circadian rhythms. In mammals, circadian rhythms are generated by circadian clock within the suprachiasmatic nuclei of the hypothalamus (SCN). Light entrains circadian rhythms to the 24 h period of solar day. Information about light is conveyed from the retina to the SCN and induces expression of clock genes Period1 (Per1) and Period2 (Per2) that represent photosensitive parts of molecular circadian clockwork within SCN. Light sensitivity of Per1 and Per2 within SCN is temporally restricted to the subjective night phase. In addition, daily profiles of clock gene expression within SCN are modulated by daylenght, i. e. the photoperiod. The aim of our study was to elucidate how the mechanism of photic entrainment of the rat circadian clock develops during prenatal and early postnatal ontogenesis. Our results demonstrate that maternal circadian system provides information about external light to the fetal and early postnatal circadian clock. Circadian clock within the SCN of rat pups is light sensitive already at the first postnatal day. Mechanism gating the light sensitivity is present at postnatal day 3 and gradually maturates until postnatal day 10. The data suggest that the developing retina is responsive to...
Chronic insomnia and the importance of cognitive behavioral therapy in the treatment
Závěšická, Lucie ; Höschl, Cyril (advisor) ; Šonka, Karel (referee) ; Zvolský, Petr (referee)
The work is based on three studies that were made during treatment of patients with chronic insomnia. The aim was to contribute to knowledge that leads to the selection of appropriate treatment for patients with chronic insomnia. The study is primarily concerned with various aspects of cognitive-behavioral psychotherapy and particularly objectifying treatment outcomes.
Role of dopaminergic and serotonergic neurotransmission in animal models of schizophrenia
Páleníček, Tomáš ; Höschl, Cyril (advisor) ; Papežová, Hana (referee) ; Šulcová, Alexandra (referee) ; Zvolský, Petr (referee)
The dissertation presents the results of our studies on animal models of psychosis. In the pharmacological model parameters are evaluated by behavioral and electrophysiological correlates of which are subject to influence by direct modification of the serotonergic and dopaminergic neurotransmission.
Schizophrenia, diabetes and 2nd generation antipsychotics
Pastucha, Miroslav ; Höschl, Cyril (advisor)
Choosing a theme for a thesis on 3.lékařské UK faculty facilitated by that individual clinics, institutes and departments already offer students the topics more or less established research programs. In addition, of course, there is still a possibility for the student himself devised a problem that will be paid. I was determined to choose topic that will be in the field of psychiatry, because this subject I find interesting and serious I am thinking that my focus after school might be based in this direction. Teaching psychiatry, which I attended in Prague Psychiatric Center, left me very positive impression of this device, both in terms of clinics and research work, and mainly from physicians access to patients as well as science. I was therefore glad that I had the opportunity to working on his thesis on the grounds of the institution. The association of two serious illnesses, schizophrenia and diabetes mellitus, was for me, up until I started to this thesis, virtually unknown. During internship in a psychiatric clinic, but I was surprised observed that many patients with schizophrenia are obese and they themselves admitted that the therapy of certain drugs feel increased appetite. I expected, therefore, that the pathogenesis of this problem will about moving in this direction, which is partly shown. I...

National Repository of Grey Literature : 30 records found   1 - 10nextend  jump to record:
See also: similar author names
Interested in being notified about new results for this query?
Subscribe to the RSS feed.