National Repository of Grey Literature 7 records found  Search took 0.00 seconds. 
Gender differences in behavioral changes induced by latent toxoplasmosis
Lindová, Jitka ; Flegr, Jaroslav (advisor) ; Špinka, Marek (referee) ; Ditrich, Oleg (referee)
Summaryof resultsofpresentedresearch Toxoplasmagondiiis a protozoanparasiteinfectingabout30%ofour population.After a shortphaseof acuteinfection,the parasitosistums into the lifelong latents.tagewhich is usuallyconsideredasymptomatic.However,in thestudiesperformedby our researchteam, latenttoxoplasmosiswasťoundto havespecificeffectson personality,behavior,morphology andphysiotogy.Interestingly'in manyaspects,theseeffectswereclearlygender-dífferent. My thesis was motivatedby results of previous questionnairestudies which found toxoplasmosisto haveoppositeinfluenceon men's and women'spersonalitytraitswarmth, conscíentiousnessandvigilancemeasuredby Cattell's16PersonalityFactorQuestionnaire (Flegretď. L996,1999,2000'FlegrandHavlíček1999'FlegrandHrdý 1994).Bothinfected womenand men werealso foundto score lower in novelryseeking(Skallová et al. 2005' Flegretal.2003). The resultof lowernoveltyseekingwas confirmedby thefirst studyperformedwith my contribution(lt{ovotnáet al. 2005).Moreover,this studyshowedthat regardingnovelty seeking,similar changeswere observedin subjectsinťectedby cytomega|ovirus.This was interprétedasevidenceforthehypothesisthatbehavioral/personalityshifu inducedby latent toxoplasmosiscouldbenonspecificchanges,causedby mildchronicbraininfections.Lower novelty seeking is thought to be associated...
Molecular and serologic diagnosis of infections caused by Trichobilharzia
Vaščiková, Michaela ; Horák, Petr (advisor) ; Ditrich, Oleg (referee)
Cercariae of the genus Trichobilharzia can penetrate not only the skin of definitive hosts (ducks), but they are also able to penetrate the skin of accidental hosts (mammals). As a result of the penetration, the inflammatory response known as cercarial dermatitis appears. The goal of our thesis is to detect parasite DNA in the serum and cerebrospinal fluid of infected ducks, and also in the serum of infected mice. By using PCR with primers designed for a tandem repeated sequence, we were able to detect 1 femtograms of parasite DNA isolated from sera of infected ducks. We were able to amplify parasite DNA only from 16 samples of sera and cerebrospinal fluid of the infected ducks, but we were not able to do so with the serum of mice. Sera of infected mice were also tested by ELISA and Western blot. The homogenates of T. regenti (TRhc), T. szidati (TShc) and S. mansoni (SMhc) cercariae were selected as an antigen. The results showed progressive increase in the level of IgM antibody from 10 days after 1st infection and also increase of the level of IgG from the 2nd infection. 10 days after the 4th infection, the level of IgM and IgG gradually declined, but the level of antibodies 100 days after the 4th infection was still higher if compared to uninfected mice. Results from Western blot analysis...

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