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Leishmania infantum in south Turkey
Bublíková, Jitka ; Nohýnková, Eva (referee)
Leishmaniasis is a serious disease caused by protozoans of the genus Leishmania. It occurs in different levels of severity from mild, where the parasite causes ulcers on the skin to severe, where the internal organs are attacked and can result in death of the patient. It is transmitted small bloodsucking insects of the genus Phlebotomus. Our research was focused on outbreak of cutaneous leishmaniasis in the Cukurova region in the south Turkey. For the causative agent, there was largely regarded Leishmania tropica. In our study, we demonstrated as the causative agent Leishmania infantum, which is often described in visceral form. The negative result of rK39 test confirmed non-visceral form of the disease. L. infantum was also detected in the most abundant sand fly species, Phlebotomus tobbi. We have shown that some P. tobbi were engorged with human blood and any sand fly did not contain dog's blood. Therefore, we assume anthroponotic cycle in the focus, even L. infantum is usually a zoonosis. In the rigorous thesis, I tried to summarize the current knowledge about the outbreak of cutaneous leishmaniasis in the Cukurova region. Follow-up studies confirmed the abundance of P. tobbi through the season, but also revealed the high incidence of P. perfiliewi during the season. It could be also involved in...

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