National Repository of Grey Literature 58 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
Human hearing sensitivity assesment
Tinka, Dominik ; Sekora, Jiří (referee) ; Škutková, Helena (advisor)
Bachelor thesis aims to evaluate changes of sensitive human hearing through created mobile application. According to obtained teoretical knowledges mobile application provide audiometrical measurements. In connection with this is described adjustments of sound outcomes of mobile, which is set in pursuance of calibrate unit. In the next part is described methodics of measuring and processing measured data. Static evaluation is processed on collected measured data from one proband and group of probands. Measurements on one proband were repeated for couple of days. The end of this thesis discusses about obtained results, which challenges the hypothes about sensitivity of hearing.
Testing of Recognizing Spatial Intelligence
Malý, Tomáš ; Škutková, Helena (referee) ; Sekora, Jiří (advisor)
This thesis deals with measurement issues in psychology, specifically online diagnostics of spatial abilities. It gives a brief look on psychological construct of intelligence and methods of measuring it, currently in the context of the most spread theory of intelligence C-H-C (Cattell- Horn-Carroll). This thesis focuses on ability called „Visualization“, that is understood as the ability to process visual perceptions and manipulate them in our imagination. The thesis includes functional software, which is made for online computer testing of spatial abilities in children of preschool, or school age.
Mobile application for psychodiagnostics of preschool children
Guryča, Ondřej ; Smíšek, Radovan (referee) ; Škutková, Helena (advisor)
This bachelor thesis deals with the possibility of preschool children psychodiagnostics using a smartphone application. It is focused on the principle of psychodiagnostics and its different approach to preschool children psychodiagnostics, there are also described tests used in nowaday psychodiagnostics. In the next part is presented the current implementation of the OS Android application with chosen tests. At the end is an explanation of the way of evaluating data and recommendations for using the app.
Pozitive and negative selection of mitochondrial genome
Svoboda, Matěj ; Škutková, Helena (referee) ; Maděránková, Denisa (advisor)
This bachelor thesis deals with positive and negative selection detection in mitochondrial genome of invertebrates and vertebrates. The component of this paper is to interpret the theory of evolution and evolution models. The main objective of this bachelor thesis is to formulate the algorithm package for a positive and negative selection detection in a program environment, RStudio. Consequently, outcomes of algorithm are compared to values acquired by tool PAML.
Analysis of genetic variability in sequencing data of Treponema strains
Bartoň, Vojtěch ; Škutková, Helena (referee) ; Maděránková, Denisa (advisor)
This diploma thesis is dealing with methods of identification genetic variability in sequencing data. The resarch is targeted to bacterial strains of Treponema pallidum. The sequencing was performed by Illumina platform. There is a proposition of method to identificate variable spots in resequenced genomes and their analysis and comparation across all processed genomes.
Automatic genotyping of bacteria by rep-PCR
Pelikánová, Veronika ; Maděránková, Denisa (referee) ; Škutková, Helena (advisor)
This thesis deals with automatic bacteria genotyping by rep-PCR method. Its theoretical part presents various methods of DNA typing, basic information on electrophoresis and modern electrophoretic approaches, including their problems, misleading data distortion. In order to automate typing, there has been introduced a program for phylogenetic sample classification from rep-PCR, also applicable for data from chip capillary electrophoresis. The program consists of three main parts: digitization, bandmatching and clustering apparatus to bacterial type classification. The result of the algorithm is a phylogenetic tree, which indicates the cluster of sapmles according to bacterial type. The program has a graphical user interface for possible use in the Children's Hospital. Finally, the program is tested with data from the Children´s Hospital.
Determination of genetic differences of biological DNA sequences
Sliž, Ladislav ; Škutková, Helena (referee) ; Provazník, Ivo (advisor)
Work on determining the genetic diversity of biological signal aligning DNA sequences, will address a brief description of the composition of DNA. Following is basic information on the bioinformatics analysis. Then the work will describe the possibility of aligning DNA sequences. Work will focus primarily on global Needleman-Wunsch algorithm and local Smit - Watermanovův algorithm. Furthermore, this work will focus on aligning DNA sequences using methods CGR and FCGR. At the end of the work will describe the practical application of identifying genetic differences by aligning the sequences.
Measurement of human reaction time
Vykydal, Václav ; Škutková, Helena (referee) ; Smíšek, Radovan (advisor)
This thesis is focused on the evalution of reaction time using the android application made at MIT App Inventor. The objects will be tested for visual and auditory reaction time and the results will be statistically evaluated. Testing will involve different age groups.
Mobile genetic elements detection by genomic signal processing
Nováková, Jarmila ; Sedlář, Karel (referee) ; Škutková, Helena (advisor)
Mobile genetic elements are occupied by this project. It is aimed at their features, which can be used for their detection. It also deals with issue of conversion of symbolic sequence into numerical form. Classifications of mobile genetic elements are explained, basic types of mobile genetic sequences are described, and principles of numerical maps and detection in symbolic represetation are also clarified. Conversion of symbolic genetical sequences by chosen numerical map and calculation of normalized correlation values for set of mobile genetic elements are compiled. Analysis of the mobile genetic elements properties is performed for design of detector. The library of themes is created at the end for usage by designed detector.
Digital image analysis of mitotic chromosomes
Jaroš, Luboš ; Vítek, Martin (referee) ; Škutková, Helena (advisor)
The development in modern medicine has allowed to study human genome and detect predispositions to several diseases. One of very promising techniques is the analysis of human karyotype, i.e., the number and appearance of chromosomes in the cell nucleus. The most important step in the karyotype analysis is the chromosome detection and categorization. In this work, a new algorithm for detection of chromosomes from an image of microscopic DNA sample and their categorization into seven groups was developed. The algorithm was implemented in Matlab. The accuracy of segmentation and classification was tested on a set of images from two databases with 117 and 38 images, respectively. The sensitivity of the developed segmentation reached 88% while the value of positive predictivity of segmentation reached 92%. The success rate of chromosome pairing achieves 77%.

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