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Quantification of viscoelastic properties of porcine aortic walls in dependence on direction of strain, distance from heart and age of donors
Tobias, Miriam Christine ; Ďoubal, Stanislav (advisor) ; Klemera, Petr (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Department of Biophysics and Physical Chemistry on direction of strain, distance from heart and age of donors Mechanical behaviour of biological structures depends on elastic, as well as viscous properties of biological materials. The main problem is the identification of models and the estimation of their parameters. Practically, the static deformation responses are combined with various dynamic characteristics. In most cases, transient and frequency characteristics or creep curves are being used in available appliances. Apparatuses based on these principles are technically complicated and expensive. One aim of our research was to alleviate this situation. Furthermore our aim was to investigate in a phenomenological study quantitative differences in viscoelastic parameters of porcine aortic walls in dependence on distance to heart, direction of strain, and age of donors. For that reason we developed appliance based on measurements of self-oscillation of sample of material simulating the dynamic loading to get information about the relationship between harmonic stress and loading, and simulating dissipation of energy in real systems. In order to obtain relevant information from the experiment, the load and deformation...
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Quantification of viscoelastic properties of porcine aortic walls in dependence on direction of strain, distance from heart and age of donors
Tobias, Miriam Christine ; Ďoubal, Stanislav (advisor) ; Klemera, Petr (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Department of Biophysics and Physical Chemistry on direction of strain, distance from heart and age of donors Mechanical behaviour of biological structures depends on elastic, as well as viscous properties of biological materials. The main problem is the identification of models and the estimation of their parameters. Practically, the static deformation responses are combined with various dynamic characteristics. In most cases, transient and frequency characteristics or creep curves are being used in available appliances. Apparatuses based on these principles are technically complicated and expensive. One aim of our research was to alleviate this situation. Furthermore our aim was to investigate in a phenomenological study quantitative differences in viscoelastic parameters of porcine aortic walls in dependence on distance to heart, direction of strain, and age of donors. For that reason we developed appliance based on measurements of self-oscillation of sample of material simulating the dynamic loading to get information about the relationship between harmonic stress and loading, and simulating dissipation of energy in real systems. In order to obtain relevant information from the experiment, the load and deformation...
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