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	Extracellular space size and geometry in the brain of APP23 mice representing a model of Alzheimer´s disease Mazel, Tomáš ; Antonova, Tatiana ; Meyer-Luhmann, M. ; Staufenbiel, M. ; Jucker, M. ; Syková, Eva The decrease in ECS size observed during aging might contribute to increased extracellular amyloid concentration and deposition in APP23 mice. Úplný záznam
	Alterated diffusion parameters in the brain with kaolin-induced hydrocephalus Fiala, Jindřich ; Antonova, Tatiana ; Voříšek, Ivan ; Syková, Eva Compression of the ECS in the cerebral cortex following induction of hydrocephalus, slows down the diffusion of neuroactive substances in hydrocephalic tissue. Úplný záznam
	Extracellular space volume fraction and geometry in human cortex and glial tumors Homola, Aleš ; Vargová, Lýdia ; Zámečník, J. ; Tichý, M. ; Beneš, V. ; Syková, Eva Ecs diffusion parameters in human temporal cortex similar to those previously determined in rat cortex. Volume fraction ? and tortuosity ? are increased in astrocytic gliomas and the higher the glioma´s WHO grade the greater the ECS volume and tortuosity increase. Migration and invasiveness correlate with an increase in ECS volume. Úplný záznam
	Learning, MRI and structural changes of the rat hippocampus 1 ro 12 months after irradiation with the leksell gamma knife Náměstková, Kateřina ; Liščák, R. ; Herynek, V. ; Burian, M. ; Jirák, D. ; Hájek, M. ; Brožek, G. ; Mareš, V. ; Syková, Eva The lower the dose of irradiation with the LKG, the more delayed are the structural and functional changes in hippocampus. Úplný záznam
	Neuron-glia communication by extrasynaptic transmission Syková, Eva Dynamic changes in ECS ionic composition, volume and geometry accompany neuronal activity, neuronal loss, glial development and proliferation, aging, CNS injury, anoxia/ischemia, spreading depression, tumors, inflammation dyemyelination and many other brain pathological states. Úplný záznam
	Changes in astrocytic structure in rat hippocampus evoked by activation of glutamate receptors and learning Šimonová, Zuzana ; Náměstková, Kateřina ; Vargová, Lýdia ; Syková, Eva Stimulation by NMDA application or learning alters astrocytic structure. Úplný záznam
	Biocompatible polymer hydrogels usable for nervous tissue regeneration Lesný, Petr ; DeCroos, Jane ; Přádný, Martin ; Vacík, Jiří ; Syková, Eva PHPMA hydrogel matrices have the ability to induce tissue formation within them and therefore support the regeneration of nervous tissue. Úplný záznam
	Diffusion and MRS in a rat cortex after traumatic injury Voříšek, Ivan ; Herynek, V. ; Burian, M. ; Hájek, M. ; Niclay, K. ; Syková, Eva An increase in diffusion barriers, manifestes by a decrease of both ADCTMA and ADCW, occurs throughout the entire cortex of the wounded hemisphere. These changes are related to astrogliosis and to an accumulation of extracellular matrix molecules without significant changes in ECS volume. Úplný záznam
	Suppression of 2f1-f2 distortion product otoacoustic emissions by electrical stimulation of the inferior colliculus in guinea pigs Popelář, Jiří ; Mazelová, Jana ; Syka, Josef Electrical stimulation of certain parts of the IC resulted in the depression of the DPOAE amplitude by 0.1-2 dB. The value of maximal DPOAE suppression was similar to the DPOAE suppression produced by acoustical stimulation of the contralateral ear. Our results indicate that electrical stimulation of the external cortex of the IC can activate the efferent system and produce DPOAE suppression by similar mechanisms as does acoustical stimulation of the contralateral ear. Úplný záznam
	A behavioral and electrophysiological study of the effects of noise exposure on auditory function in rat Rybalko, Natalia ; Mazelová, Jana ; Syka, Josef The values of the gap detection threshold doubled after exposure to 110 dB SPL and quadrupled after exposure to 115-120 dB SPL. GDT recovered to the original values during 1-2 weeks. Increased gap detection thresholds after noise exposure appear connected with elevated hearing thresholds, the deterioration in the performance of some animals in behavioral rasts after strong intensity noise (120 dB SPL) may signal the occurrence of tinnitus in these animals. Úplný záznam

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