Doctoral theses

Doctoral theses 14,205 records found  previous11 - 20nextend  jump to record: Search took 0.00 seconds. 
IT Security in Biomedicine.
Schlenker, Anna ; Šárek, Milan (advisor) ; Nakládalová, Marie (referee) ; Brechlerová, Dagmar (referee)
Title: IT Security in Biomedicine Author: Ing. Anna Schlenker Supervisor: Ing. Milan Šárek, CSc. Abstract: The aim of this work is to propose a solution to the biomedical data security strategy. The work provides an overview of the most commonly used biometric methods designed to identify or authenticate users. From these methods, the keystroke dynamics was chosen and used in the application solution. The reliability of this method has been tested by classical and modern classification methods. The greatest benefit of the work is the use of the created application in combination with the measurement using integrated electromyography to objectify the evaluation of the work related to keyboard typing in terms of local muscle load. Keywords: Biometrics, Data Security, Keystroke Dynamics, Local Muscle Load
Baroque sculpture workshop of Andreas Philipp and Johann Anton Quitteiner
Hořák, Martin ; Adamcová, Kateřina (advisor) ; Oulíková, Petra (referee) ; Zápalková, Helena (referee)
The Quitteiner family sculpture workshop operated in Prague from the turn of the 18th century to the year 1765. The span of its existence is delimited on one side by the arrival of its founder, Andreas Philipp Quitteiner (1679-1729), from Frýdlant in northern Bohemia, and on the other side by the death of the upholder of the family tradition, Johann Anton Quitteiner (1709-1765). During the lifetime of Quitteiner Senior the workshop built its reputation as the leading Prague- based sculpture studio. A. F. Quitteiner strengthened his position while working in the Württemberg region in 1709-1712, and then in 1713 and 1714, when he participated together with other Prague artists in decorating the palace residence at Ludwigsburg. After his return to Prague the elder Quitteiner won recognition alongside the most prominent figures of Czech Baroque sculpture F. M. Brokoff and M. B. Braun, and created his best works, including four statues on the side altars of the Holy Family and Saint John of Nepomuk in Saint Thomas's church in Prague's Lesser Quarter. Quitteiner's son Johann Anton learnt his craft in the family workshop which he took over after his father's death. The starting point for his work was the realistic style of his father. He built on this foundation, however, adding to it elements of...
Educational aspects of space perception
Novotná, Kateřina ; Hanus, Martin (advisor) ; Knecht, Petr (referee) ; Siwek, Tadeusz (referee)
The purpose of this thesis is to focus on the research of space perception. Under the term space perception is understood the widest possible meaning as a process wherein an individual creates ideas about the outside world (Siwek 2011). Space imaginations contains objects with their attributes and relations between each other. In as much as each of us creates ideas about space, then it can be assumed a relatively wide interest in different scientific disciplines, which causes an unclear scientific anchoring of terminology and methodology. Therefore, this thesis first discusses the terminology and methodology regarding the research within a geographical education. Then this thesis proceeds to the definition of key terms: mental map, cognitive map and sketch map. Mental map and cognitive map in this thesis are understood as synonyms that reflects the ideas in the memory of an individual about the outside world, whereas the sketch map is one of the methods how to collect these ideas. Furthermore, this thesis defines the methods of collecting data of subjective characteristics contained in mental maps, which can be subsequently visualised through thematic mental maps. Therefore, the following part of the thesis focuses on the sketch map and thematic mental map as a tool and a subject of geographical...
Expanding the Vocabulary of Roma Pupils in the Second Level of Primary School
Kráčmarová, Drahoslava ; Šebesta, Karel (advisor) ; Janovec, Ladislav (referee) ; Chejnová, Pavla (referee)
The work deals with the acquisition of vocabulary in the period of advanced language development in second-level primary school pupils from different socio-economic and socio- cultural backgrounds. The theoretical section summarises the basic findings as well as the existing empirical research, focusing in particular on the influence of the family environment of the individual on his/her linguistic development. It provides a complex picture of the education of Roma children in the Czech Republic at this point in time. The investigative section presents independent research into the vocabulary of pupils, with regard to selected word groups in the acquisition corpus SKRIPT2015. The texts of pupils attending schools in socially-deprived areas, or in areas under threat of social deprivation and with a strong Roma presence, are compared with the texts of pupils attending average schools. On the basis of this comparison, a picture emerges of the impact of different socio-economic and socio-cultural environments on the written language of pupils, as well as the effectiveness (or lack thereof) of the existing support mechanisms provided by educational institutions. KEYWORDS acquisition of language, advanced language development, expansion of vocabulary, education of Roma children, acquisition corpus, SKRIPT2015
Changes in reproductive behaviour in the beginning of the demographic revolution (example of Staňkov)
Bozděch, Lukáš ; Fialová, Ludmila (advisor) ; Maur, Eduard (referee) ; Velková, Alice (referee)
Changes in reproductive behaviour in the beginning of the demographic revolution (example of Staňkov) Abstract The aim of this study is to analyse reproductive behaviour of population in the Czech lands in the 19th century, a period in which demographic revolution began. The research is based on data from Staňkov, a town in southwestern Bohemia, which, unlike the majority of adjacent region, experienced a substantial industrialization in the 19th century. This resulted in a significant population growth during the analysed period. Family lists were compiled from the registers of births, marriages and deaths using the method of family reconstitution. Nuptiality, marital fertility and infant mortality were the main analysed topics. Population was also divided into groups based on social stratification and these groups were analysed to determine, whether their reproductive behaviour differed from each other. The results from Staňkov were compared to other previously studied localities in the Czech lands. This study revealed that in the 19th century changes in reproductive behaviour within social groups were quite small or negligible. Big changes in nuptiality, fertility or infant mortality in the beginning of demographic revolution can therefore be mainly attributed to the shifts in the social structure of the...
The relationship between eating habits and nutrition-related knowledge of grade nine students of elementary schools and design of nutrition education program
Kočí, Jana ; Marádová, Eva (advisor) ; Dohnal, Karel (referee) ; Fialová, Ludmila (referee)
Obesity and the number overweight of children are currently major global issues. According to the Regional Office for Europe (2006) obesity has risen three times over the last two decades worldwide. The attention is currently focused on health promotion and disease prevention among the population through comprehensive health education starting in the early age of individuals, aimed to slow down the increasing incidence of obesity and related health issues. This thesis discusses the pedagogical aspects of health, specifically the options on how to shape nutritional habits of elementary and middle school students and how to systematically deepen the required knowledge about healthy nutrition by implementation of nutrition education programs. The purpose of this study was to determine the relationships between dietary habits and healthy nutrition knowledge of grade nine students in elementary schools from the South Bohemian region in Czech Republic. A validated Nutritional survey and Nutritional knowledge quiz were designed to determine the relationship between knowledge and behavior of grade nine students from South Bohemia elementary schools. The validity of the Nutritional survey and the Nutritional knowledge quiz were tested using analytical analysis of all survey and test items and examining...
Speciation genomics in nightingales
Mořkovský, Libor ; Reifová, Radka (advisor) ; Macholán, Miloš (referee) ; Piálek, Lubomír (referee)
Speciationisusuallyaslowprocessoccurringoverthousandstomillionsofyears.Thismakes speciation research difficult because no direct observation or manipulation is possible. At best, we can gain some insight by inferring the population history and structure in very fine detail by investigating genetic markers in multiple individuals of the nascent species. Today, speciationresearchisinanunprecedentedpositionthankstotheadventofhigh-throughput sequencingmethods,whichmakeiteasier and cheaper than ever before to evaluate multiple markers in many individuals. Speciation is not a straightforward process that happens in the same way every time, but rather a phenomenon occurring when genetic and ecological circumstancesactinginsymphonyultimatelyleadtoreproductiveisolationoftwosubpopula- tions. This is why it is important to study multiple model systems to understand the general principles behind speciation. We worked with two species of nightingales (Luscinia luscinia andL.megarhynchos)thatdivergedapproximately1.8Mya,likelyduetoglacialfluctuations in Europe. Our main goal was to use these new high-throughput sequencing methods to (1) detect interspecific hybrids between the species, (2) estimate levels of interspecific gene flow,(3)findareasofthenightingalegenomethatunderliereproductiveisolationand,finally, (4)...
Relation between the reperfusion of pulmonary arteries after an acute pulmonary embolism to the development of chronic thromboembolic pulmonary hypertension.
Mrózek, Jan ; Jansa, Pavel (advisor) ; Maxová, Hana (referee) ; Hutyra, Martin (referee)
Relation between the reperfusion of pulmonary arteries after acute pulmonary embolism to the development of chronic thromboembolic pulmonary hypertension Incomplete resolution of thromboemboli following acute pulmonary embolism (PE) is a key factor in development of chronic thromboembolic pulmonary hypertension (CTEPH). In our study, we evaluated the incidence, risk factors and clinical impact of incomplete reperfusion after acute PE. Study population and methods: 85 patients after the first acute PE were assessed clinically and by pulmonary scintigraphy and echocardiography at month 6, 12 and 24 after an acute PE. Results: Incomplete reperfusion was detected in 23.5 % of patients after 6 months, in 24.9 % of patients after 12 months and in 18.6 % of patients after 24 months. At month 6, patients with incomplete reperfusion were more obese when compared with patients with normal reperfusion BMI 30.8 vs 28.3 kg/m2 ; p=0.012) and their initial hemoglobin levels were higher (143.0 vs 136.0 g/l; p=0.012). Similar results were observed at month 12 - patients with residual perfusion defects were more obese (BMI 31.1 vs 28.5; p=0.016) with higher initial hemoglobin levels (144.0 vs 136.0; p=0.007). Patients with incomplete reperfusion at month 24 were significantly older (67.7 vs 55.0 years; p=0.02), their...
Legal regulation of climate protection following the adoption of the Paris Agreement
Balounová, Eva ; Stejskal, Vojtěch (advisor) ; Tomoszková, Veronika (referee) ; Průchová, Ivana (referee)
Legal regulation of climate protection following the adoption of the Paris Agreement Abstract The Paris Agreement was adopted on 12 December 2015 and became effective on 4 November 2016. The Agreement's central aim is to keep the increase in global average temperature well below 2žC above pre-industrial levels and to limit the increase to 1.5žC. The Agreement starts to apply in 2020. Under the Paris Agreement, each Party must communicate its nationally determined contributions, which will help to achieve the purpose of the Agreement. The aim of this thesis is to analyse the development of the legal protection of the Earth's climate system in the European Union after the adoption of the Paris Agreement. Part One is subdivided into four chapters. The first chapter is introductory and provides an overview of basic terminology, scientific knowledge and observed changes in climate and their impact. Chapter Two deals with the subject matter of international climate change law. Chapter Three deals with the legal sources of international law, in particular with international conventions. Legal principles are described there as well. Chapter Four looks at the historical development of the international protection of the climate. Also, it focuses on the analysis of the Paris Agreement. This chapter describes the...
Maintenance of chromosomes integrity in Giardia intestinails as a model organism.
Uzlíková, Magdalena ; Nohýnková, Eva (advisor) ; Lalle, Marco (referee) ; Stejskal, František (referee)
Giardia intestinalis is a protozoan causing diarrhea worldwide. Beside its medical importance, it is evolutionary distant protist with two nuclei within a cell adapted for parasitic life in the environment poor of oxygen. Its genome is small and compact in term of gene content and size. It is therefore an attractive model organism for studies of minimal requirements for cellular processes. Present work brings new partial information on different levels of chromosome integrity maintenance of this parasite. Our study presents characteristics of chromosome termini and their protection. We localized telomeres during all stages of the trophozoite cell cycle and determined the length of Giardia telomeres ranging from 0.5 to 2.5 kb, we proved an existence of an active telomerase enzyme synthesizing telomeric repeats in in this parasite, despite the fact that giardial telomerase is structurally divergent. Present data support the view that the chromosomal termini in Giardia are maintained in a conservative manner that is common to other eukaryotes. We described effects of commonly used drug for treatment of anaerobic infections, metronidazole, on DNA and cell cycle progression in susceptible and resistant cell lines. Incubation of cells with this drug causes phosphorylation of histone H2A in cell nuclei...

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