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Lithyalin and glazed glass of Friedrich Egermann and Buquoy Hyalit glass - a phenomenon of the Biedermeier and the Second Rococo era in the Czech lands.
Schneiderová, Daniela ; Schöttner, Jan (advisor) ; Wittlich, Filip (referee)
This thesis examines a specific part of the Czech glass production from twenties to forties of the 19th century. It focuses specifically on the production of glassworks at Novohradsko in South Bohemia where the black and red hyalit glass was been made. Next it examines the works of glass technologist Bedřich Egermann in Polevsko and (Nový) Bor, where he rediscovered and implemented the production of glaze refined glass and also discovered and made the first lithyalin glass. These new made or rediscovered technological methods reflected the change of taste in the Biedermeier and Second Rococo era when the glass production in the Czech lands has reached world class. Not only that it could cope with current English and French production, but it surpassed them in many regards. Producing opaque and glazed glass was a significant deed that contributed to increasing the reputation of already great Czech glassmaking in this era. Keywords Buquoys, Egermann, hyalit, glazes, opaque glass, glass
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Significance of the major histocompatibility complex for organ transplantation
Ilina, Liudmila ; Slavčev, Antonij (advisor) ; Grobárová, Valéria (referee)
The major histocompatibility system is a region in the human genome located on chromosome 6. HLA genes encode polymorphic cell-surface glycoproteins which are primarily responsible for presentation of self and non-self antigens to T cells. When the T lymphocyte recognizes the MHC-peptide complex as foreign, it activates effector components of the innate and adaptive immune system. Therefore, mismatched HLA antigens can lead to a strong immune response against the donor's tissue. HLA laboratories support transplant programs by evaluation the HLA matching between patients and their potential donors and, based on these data, assist in the evaluation of the risk of rejection and eventual immunological complications after transplantation. The aim of this thesis is to describe the significance of the major histocompatibility complex for the occurrence of cellular and antibody-mediated rejection after solid organ transplantation and discuss the relationship between the degree of HLA matching and graft survival outcomes. Key words HLA, organ transplantation, rejection
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The effect of synthetic oxytocin on motherhood
Jendrisková, Blanka ; Kaňková, Šárka (advisor) ; Třebická Fialová, Jitka (referee)
Oxytocin falls into the group of hormones, the synchronisation of which is very important for a correct procedure of childbirth. It is a hormone that has both peripheral and central effects. Its synthetic version belongs to the group of uterotonics, which are used in obstetrics. Synthetic oxytocin is administered both to induce labour or accelerate it directly in its course and after delivery as a prevention of postpartum hemorrhage. However, synthetic oxytocin administered in this way may affect the initiation of breastfeeding and further postpartum adaptation of both mother and child. For example, impaired primitive neonatal reflexes in newborns or greater propensity to postpartum depression in mothers have been observed following administration of synthetic oxytocin.
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Seven Corporal Works of Mercy and Seven Deadly Sins in Czech Medieval Arts
Eichlerová, Eliška ; Vymazalová, Marie (advisor) ; Royt, Jan (referee)
The bachelor's thesis will deal with the theme of the seven-corporal works of mercy and the seven deadly sins in Czech fine art. These opposing themes develop primarily in a middle-class environment, where they were supposed to appeal to the moral life of the middle-class people. The first part of this thesis will discuss the development of the doctrine of the seven deadly sins in the Middle Ages. The variability of approaches to the seven sins will also be revealed by a comparison with the development of the doctrine of the virtues, where it is also possible to show the starting points for the formation of the medieval teaching on the seven-corporal works of mercy. The second part deals with the analysis of individual sins and acts of mercy, their meaning, and the way they are depicted. In the third part, I will also focus on individual examples of the depiction of this iconography in European art, and we will mention a few important works, especially from the High and Late Middle Ages. Following on from European art, the last chapters will focus on individual examples of the seven-corporal works of mercy and the seven deadly sins in the Czech environment, especially in the book painting and monumental mural.
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School textbooks and their use in practice: the role of students in the evaluation of textbooks and geographical content
Kulma, Natanael ; Marada, Miroslav (advisor) ; Cimová, Tereza (referee)
The present bachelor thesis deals with the issue of school textbooks. In the theoretical part, the textbook is clearly defined in terms of its privileged position among educational resources, its internal structure and the functions to which it is adapted. Furthermore, the extent to which it is used, and the way in which it is used in practice by teachers and pupils, is mapped out. Finally, the role of the learner as the evaluative subject of textbooks is presented, and specific recommendations for research and design of textbooks with the aim of increasing their use by learners are outlined. The practical part presents insights into the background of primary school pupils in order to test the theoretical assumptions regarding pupils' experiences of textbook use, their evaluation of the textbook and their preferred geographical themes in the content of the geography textbooks.
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Tolerogenic dendritic cells as immune interventions in prevention or therapy of type 1 diabetes
Petrovčíková, Diana ; Funda, David (advisor) ; Hrdý, Jiří (referee)
The main aim of this work is to refer a recent summary of the opportunities and pitfalls of the application of tolerogenic dendritic cells in the prevention or therapy of type 1 diabetes (T1D). Tolerogenic dendritic cells (TolDCs) represent a potential tool for the treatment of allergies, transplant rejections and autoimmune diseases, including T1D, due to their capability to specifically inhibit autoimmune reactions without causing general immunosuppression. TolDCs represent a specific group of dendritic cells and are essential in establishing central and peripheral tolerance. This work presents a helpful guide to better understanding the physiology of tolerogenic DCs and an overview of in vitro generation attempts. In addition, the route of application and migration to target organs has been described. Type 1 diabetes (T1D) is a chronic disease resulting from immune-mediated destruction of the insulin-producing beta cells in the pancreas. Animal models have been invaluable in testing innovative medical treatments since the early testing of insulin in dogs almost a century ago. Animal models of type 1 diabetes (T1D) enable the study of the mechanisms underlying its pathogenesis and the potential development of therapeutic interventions. However, there are still significant gaps in our general...
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