TY - GEN TI - Modeling of nucleolar self-assembly T3 - Proceedings of the International Conference on Modelling and Simulation 2010 AU - Blažíková, Michaela AB - Mammalian cell nucleoli disassemble at the beginning of mitosis and reassemble again during telophase and the early G1. Dynamics of this process was studied using a model based on entropy driven self-assembly of pre-ribosomal particles generated in a single biosynthetic source. Monte Carlo simulations revealed that such model can explain formation of a large aggregate, a nucleolus, in the vicinity of the source. We examined influence of nucleoplasm properties on dynamics of the aggregate formation. SN - 978-80-01-04574-9 UR - http://www.nusl.cz/ntk/nusl-42162 UR - http://hdl.handle.net/11104/0191512 A2 - Heřman, P. A2 - Malínský, Jan LA - eng KW - Monte Carlo simulations PY - 2010 PB - Ústav experimentální medicíny, Vídeňská 1083, 142 20 Praha 4, http://www.iem.cas.cz/ ER -