Original title: A novel nanospray liquid junction interface for versatile CE-MS
Authors: Křenková, Jana ; Haselberg, R. ; Somsen, G. W. ; Foret, František
Document type: Papers
Conference/Event: CECE 2016. International Interdisciplinary Meeting on Bioanalysis /13./, Brno (CZ), 20161017
Year: 2016
Language: eng
Abstract: In this work we present a new polyimide-based liquid junction nanospray interface, combining the advantages of sheath flow and sheathless designs. The liquid junction interface was prepared as a hybrid microfabricated plastic liquid junction sprayer allowing to perform analysis in standard (30-100 micro m ID) separation capillaries. The interface incorporates a self-aligning port for coupling of the separation capillary as well as ports for automated flushing of both the liquid junction and the separation capillary. The interface permits performing CE both with and without electroosmotic flow. The use of large bore capillaries allows injection and preconcentration of larger sample volumes, favoring detection sensitivity. Different compositions of the spray liquid and BGE can be used when needed.
Keywords: capillary electrophoresis; liquid junction interface; mass spectrometry
Project no.: GBP206/12/G014 (CEP), GJ16-09283Y (CEP)
Funding provider: GA ČR, GA ČR
Host item entry: CECE 2016. 13th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-4-4

Institution: Institute of Analytical Chemistry AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0265739

Permalink: http://www.nusl.cz/ntk/nusl-261683


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Research > Institutes ASCR > Institute of Analytical Chemistry
Conference materials > Papers