Název:
A novel nanospray liquid junction interface for versatile CE-MS
Autoři:
Křenková, Jana ; Haselberg, R. ; Somsen, G. W. ; Foret, František Typ dokumentu: Příspěvky z konference Konference/Akce: CECE 2016. International Interdisciplinary Meeting on Bioanalysis /13./, Brno (CZ), 20161017
Rok:
2016
Jazyk:
eng
Abstrakt: In this work we present a new polyimide-based liquid junction nanospray interface, combining the advantages of sheath flow and sheathless designs. The liquid junction interface was prepared as a hybrid microfabricated plastic liquid junction sprayer allowing to perform analysis in standard (30-100 micro m ID) separation capillaries. The interface incorporates a self-aligning port for coupling of the separation capillary as well as ports for automated flushing of both the liquid junction and the separation capillary. The interface permits performing CE both with and without electroosmotic flow. The use of large bore capillaries allows injection and preconcentration of larger sample volumes, favoring detection sensitivity. Different compositions of the spray liquid and BGE can be used when needed.
Klíčová slova:
capillary electrophoresis; liquid junction interface; mass spectrometry Číslo projektu: GBP206/12/G014 (CEP), GJ16-09283Y (CEP) Poskytovatel projektu: GA ČR, GA ČR Zdrojový dokument: CECE 2016. 13th International Interdisciplinary Meeting on Bioanalysis, ISBN 978-80-904959-4-4
Instituce: Ústav analytické chemie AV ČR
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Informace o dostupnosti dokumentu:
Dokument je dostupný v repozitáři Akademie věd. Původní záznam: http://hdl.handle.net/11104/0265739