Original title: Capillary electrophoretic chiral analysis and estimation of helix inversion barrier of helquats using randomly sulfated cyclodextrins as chiral selectors
Authors: Kašička, Václav ; Koval, Dušan ; Sázelová, Petra ; Severa, Lukáš ; Adriaenssens, Louis ; Vávra, Jan ; Teplý, Filip
Document type: Papers
Conference/Event: International Symposium Advances in Chromatography and Electrophoresis and Chiranal, Olomouc (CZ), 2012-06-11 / 2012-06-14
Year: 2012
Language: eng
Abstract: Capillary electrophoresis in acidic sodium phosphate background electrolyte, pH 2.4, with randomly sulfated alpha-, beta- and gamma-cyclodextrins as chiral selectors was employed for fast, high-resolution separation of enantiomers of a series of 24 helquats, a new class of N-heteroaromatic dicationic helicene-like species. The developed CE methodology will be utilized in the further investigation of helquats, e.g., in evaluation of their preparative enantioresolution procedures, in monitoring of their racemization and determination of interconversion barrier of helquat enantiomers.
Keywords: capillary electrophoresis; helquat chiral analysis; sulfated cyclodextrins
Project no.: GAP207/10/2391 (CEP), GA203/08/1428 (CEP), GAP206/12/0453 (CEP)
Funding provider: GA ČR, GA ČR, GA ČR
Host item entry: Acta Universitatis Palackianae Olomucensis. Facultas Rerum Naturalium. Chemica 50S, ISBN 978-80-244-3115-4, ISSN 0232-0061

Institution: Institute of Organic Chemistry and Biochemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0216659

Permalink: http://www.nusl.cz/ntk/nusl-136051


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Research > Institutes ASCR > Institute of Organic Chemistry and Biochemistry
Conference materials > Papers